Feb 01, 2023  
2019-2020 Undergraduate Academic Catalog 
2019-2020 Undergraduate Academic Catalog [ARCHIVED CATALOG]

Add to Portfolio (opens a new window)

EB 3810 - Tissue Engineering

3 lecture hours 0 lab hours 3 credits
Course Description
This course covers the up-to-date fields of tissue and regenerative engineering, including scaffold design and fabrication, microfabrication technology in tissue engineering, product and process design, and clinical translation of engineered tissues/organs. Topics range from stem cells and embryogenesis, scaffold design and fabrication, organ-on-chips, bioreactors, vascularization, bioprinting, skin tissue engineering, bone/cartilage tissue engineering, cardiovascular tissue engineering, neural tissue engineering, tissue-engineered product manufacturing to clinical translation and ethical issues in tissue and regenerative engineering. (prereq: EB 2250  or equivalent)
Course Learning Outcomes
Upon successful completion of this course, the student will be able to:
  • Understand the molecular and cellular basis of tissue formation
  • Understand various microfabrication technologies in tissue engineering
  • Design scaffolds for tissue engineering
  • Understand the strategies for tissue engineering in different organ/tissue systems: skin, bone/cartilage, cardiovascular and neural
  • Understand and identify the regulatory requirements and ethical issues during clinical translation of tissue engineered products
  • Integrate chemistry, biology, and biomaterials to provide potential tissue engineering products to human health problems

Prerequisites by Topic
  • Biocompatibility
  • Biodegradation

Course Topics
  • Cells for tissue engineering
  • Clinical grade production of MSCs        
  • Bioscaffold for tissue engineering
  • Scaffold design and fabrication
  • Bioreactors for tissue engineering                           
  • Controlled release strategies in tissue engineering
  • Tissue fabrication technology: Microfabrication 
  • Scaffold Design and Fabrication: Organoids and organs-on-a-chip
  • Scaffold design and fabrication: Bioprinting
  • Scaffold design and fabrication: Decellularization  
  • Scaffold design and fabrication: Vascularization
  • Skin tissue engineering
  • Bone and cartilage tissue engineering
  • Neural tissue engineering
  • Cardiovascular tissue engineering 
  • Product and process design: Toward industrial TE manufacturing
  • Clinical translation of tissue engineering
  • Ethical issues in tissue engineering

Dr. Wujie Zhang

Add to Portfolio (opens a new window)