Sep 27, 2022  
2019-2020 Undergraduate Academic Catalog 
    
2019-2020 Undergraduate Academic Catalog [ARCHIVED CATALOG]

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CH 2251 - Organic Chemistry for Life Sciences

3 lecture hours 2 lab hours 4 credits
Course Description
The course concisely focuses on what students need to know in organic chemistry in order to continue with biochemistry in the next quarter. Basic nomenclature rules will be introduced. Important functional groups involved in biological molecules will be studied. This includes alcohols, amines, amides, aldehydes and ketones, carboxylic acids and their derivatives. The structures and chemistries of amino acids, proteins, nucleic acids, carbohydrates, and lipids will be introduced. This will help you develop the foundation for biochemistry and will also help you understand the structure of pharmaceutical drugs. (prereq: CH 2050 )
Course Learning Outcomes
Upon successful completion of this course, the student will be able to:
  • Name and draw structural formulas of organic compounds, describe bonding and isomerism, identify functional groups, conformations, properties of alkanes, alkenes, alkynes
  • Describe aromatic compounds and benzene structure, properties and uses
  • Classify alcohols, phenols, thiols and ethers, identify alcohol groups biological molecules  describe hydrogen bonding, chemical properties of alcohols
  • Describe physical and chemical properties of aldehydes and ketones, industrial and biologically important aldehydes and ketones
  • Describe physical and chemical properties of carboxylic acids and esters
  • Classify amines and assign names, recognize key reactions, names amines as neurotransmitters, give uses of specific biological amines like epinephrine, amphetamines and alkaloids
  • Name amides, show hydrogen bonding, give products of acid and base hydrolysis, make connection with biological amides in peptides and proteins
  • Learn classes of amino acids
  • Learn chemical structure of proteins
  • Learn chemical structure of nucleic acids
  • Learn chemical structure of carbohydrates
  • Learn chemical structure of lipids

Prerequisites by Topic
  • Classes of chemical bonds
  • Organic and inorganic compounds
  • Electronegativity and bond polarity
  • Shapes of molecules
  • Intermolecular forces
  • Chemical equation stoichiometry
  • Solutes and solvents-polar and non-polar
  • Solubility of substances in polar and non-polar solvents

Course Topics
  • Organic and inorganic compounds comparison, nomenclature of alkanes, alkenes and alkynes, isomerism, conformations, physical and chemical properties, polymers of alkenes (5 classes)
  • Aromatic compounds, benzene derivatives, properties and uses (1 class)
  • Naming and classifying alcohols, physical properties, reactions of alcohols. phenols, ether, thiol their biochemical importance, ether anesthetics (2 classes)
  • Naming aldehydes and ketones, physical properties, chemical properties: oxidation, hydrogenation, hemi-acetal. important aldehydes and ketones, chiral molecules, Fischer projections (3 classes)
  • Naming carboxylic acids and esters, physical properties, reactions of carboxylic acids and esters, alpha hydroxacids (3 classes)
  • Name amine and amides, physical and chemical properties, biological important amines (3 classes)
  • Classes of amino acids based on its chemistry-polar, non-polar, charged, reactions of amino acids (2 classes)
  • Structural levels of proteins-primary, secondary, tertiary and quaternary (2 classes)
  • Structure of nucleic acid bases, nucleotides, phosphodiester bond, DNA and RNA (2 classes)
  • Structural classes of carbohydrates-mono, di-, polysaccharides, glycoside bond (2 classes)
  • Classes of lipids-nonpolar triacylglycerol, polar phospholipids (2 classes)
  • Exams (3 classes)

Laboratory Topics
  • Organic techniques I
  • Organic techniques II
  • Reactions of unsaturated hydrocarbons
  • Alcohols & phenols
  • Aldehydes and ketones
  • Carboxylic acids and ester
  • Aspirin synthesis & testing aspirin products
  • Amino acid structure
  • Carbohydrate structure

Coordinator
Dr. Vipin Paliwal



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