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Apr 28, 2024
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PE 673 - Advanced Physiology I3 lecture hours 0 lab hours 3 credits Course Description This course is designed to cover the anatomy and physiology of select body systems. Areas covered include: cell structure and function (with an emphasis on membrane function and transporters), membrane potentials and action potentials, skeletal and smooth muscle structure and function, and cardiovascular structure and function. (prereq: At least one previous course in physiology or anatomy and physiology) Course Learning Outcomes Upon successful completion of this course, the student will be able to:
- Explain the structural and functional properties of eukaryotic cells, and how gene expression affects these properties.
- Explain the importance of movement of molecules across the cell membrane, the pathways for this movement and the factors that affect movement of these molecules.
- Explain how membrane potentials are generated and predict the changes that will occur in membrane potentials when ion concentration or permeabilities change.
- Identify the structures of the heart and name the major blood vessels.
- Explain the physical principles and physiological processes that regulate function of the cardiovascular system.
- Identify the waves of an EKG and explain what each wave represents.
- Explain the feedback loops that are active in the control of arterial pressure.
- Describe the steps involved in hemostasis, including the specific roles of platelets and clotting factors.
Prerequisites by Topic
- Undergraduate exposure to all topics.
Course Topics
- Homeostasis and cell function (1.5 class periods)
- Cell membrane and transport mechanisms and genetics (1.5 class periods)
- Electrophysiology (3 class periods)
- Skeletal muscle structure and function (1.5 class periods)
- Smooth muscle structure and function (1.5 class periods)
- Heart anatomy and muscle function (1.5 class periods)
- Cardiac channels, pumps and exchangers (1.5 class periods)
- Rhythmical excitation of the heart (1.5 class periods)
- EKG (1.5 class period)
- Anatomy and physics of the circulation (3 class periods)
- Vascular distensibility (1.5 class periods)
- Microcirculation and lymphatics (1.5 class periods)
- Local and nervous control of blood flow (1.5 class periods)
- Long-term regulation of arterial pressure (1.5 class periods)
- Hemostasis (1.5 class period)
- Exams (4 class periods)
Coordinator Ronald Gerrits
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