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Dec 04, 2024
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CH 322 - Organic Chemistry II3 lecture hours 0 lab hours 3 credits
Course Description
This elective is specially designed to meet the organic chemistry requirements for admission to medical school. The concepts learned in this class will be useful in understanding medical biochemistry and biotechnology. The principles of organic chemistry learned in Organic Chemistry I are further developed to understand in-depth reaction mechanisms. Understanding of organic reaction mechanisms will be useful in learning roles of organic molecules involved in various metabolic processes in living systems at molecular level. Organic chemistry is of immense commercial importance. It is the chemistry of dyes and drugs, paper and ink, paints and plastics, gasoline and rubber tires, the food we eat and the clothing we wear. Students will be introduced to such industrial and commercial applications of organic molecules. (prereq: CH 222 , CH 223 )
Course Learning Outcomes
Upon successful completion of this course, the student will be able to:
• identify and name types of aliphatic and aromatic hydrocarbons
• classify organic compounds by their functional groups and understand their reactivities
• understand in-depth important reaction mechanisms
• relate these reactions mechanisms with metabolic processes of the human body
• understand medical and biotechnological applications of organic chemistry
• be exposed to the industrial applications of organic molecules
• make scientific presentation on a topic related to organic chemistry and its commercial applications
• identify and classify organic polymers
Prerequisites by Topic
• none
Course Topics
• Review of basic organic chemistry: IUPAC nomenclature of alkanes and cycloalkanes, alkenes, alkynes, and arenes (1 class)
• Review of functional groups: Oxygen containing functional groups (alcohol, ether, aldehyde, ketone and carboxylic acid), Carboxylic derivatives (ester, thioester, amide), Nitrogen containing organic compounds (Amines, nitrocompounds) (2 classes)
• Reactions of Alkyl Halides: Nucleophilic substitation, SN 1 and SN 2 reactions, E1, and E2 reactions (3 classes)
• Arenes: Electrophilic substitution, nitration, sulfonation, halogenation, Friedel-crafts alkylation and acylation (4 classes)
• Aldehydes, Ketones and sugars: Reactions of aldehydes and ketones, acetals, imines in biological chemistry, stereoselective addition of carbonyls groups, oxidation of aldehydes, aldol condensation, nucleophilc addition to carbonyl group, reactions of carbohydrates (6 classes)
• Carboxylic acids: Physical properties, dicarboxylic acids, reactions of carboxylic acids, acid-catalyzed estrification, lactones, decarboxylation (5 classes)
• Amides & Amines: Basicity of amines, Reactions of amines, Alkylation, Hofmann elimination, electrophilic substitution, Nitrosation, amino acids, peptide (amide) bonds (5 classes)
• Introduction to polymer chemistry
• Special Topics: Biomedical, Biotechological and Industrial applications of organic chemistry (3 classes)
Coordinator
Vipin Paliwal
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