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Dec 04, 2024
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CH 222 - Organic Chemistry I2 lecture hours 2 lab hours 3 credits Course Description The major concepts and themes of organic chemistry are introduced in this course. Theory and laboratory work on the principles of organic chemistry, properties and interrelationships of important classes of organic compounds. The roles of such compounds in the metabolic processes are explained. Students are introduced to basic mechanisms of organic reactions and alerted to the industrial, biomedicall, academic and personal applications and uses of organic materials. (prereq: CH 200 or CH 200A or CH 200B ) Course Learning Outcomes Upon successful completion of this course, the student will be able to: • relate chemical bonding to molecular shape
• identify and name types of aliphatic hydrocarbons and have a knowledge of their properties, reactions, preparation and commercial applications
• identify and name types of aromatic hydrocarbons and have a knowledge of their properties, reactions, preparation and commercial applications
• classify organic compounds by their functional groups and have knowledge of their reactivities, and commercial applications
• understand the interrelationship of organic reactions with those of the human body and the metabolic processes essential to body function
• understand the safe handling of organic chemicals Prerequisites by Topic • Polarity, dipole moment, polar and non-polar covalent bonds, electronegativity Course Topics • Review of basic chemical concepts – shapes of molecules, bonding, isomerism, resonance, hybridization (3 classes)
• Alkanes and cycloalkanes - nomenclature, properties, synthesis, reactions (3 classes)
• Alkenes and Alkynes - nomenclature, properties, synthesis, reactions (2 classes)
• Aromatic and heterocyclic compounds - nomenclature, properties, synthesis, reactions (2 classes)
• Alcohols, esters, phenols, thiols - nomenclature, physical and chemical properties, reactions (2 classes)
• Aldehydes and ketones - nomenclature, properties, reactions, preparations (2 classes)
• Carboxylic acids - structure, properties, nomenclature, reactions (2 classes)
• Derivates of carboxylic acids - nomenclature, properties, reactions and applications (2 classes)
• Amines - properties, nomenclature, reactions, preparations. Study of naturally occurring and biogenic amines (2 classes) Laboratory Topics • Laboratory Techniques Part I-liquid-liquid extraction and melting point, Refluxing and TLC (4 hours total)
• Laboratory Techniques Part II-Simple distillation and estimation of boiling point
• Nomenclature and Functional groups of Organic Compounds, Structure representation
• Properties of Alcohols
• Synthesis of salicylic acid: Synthesis and start of recrystallization
• Synthesis of Aspirin: Synthesis and start of recrystallization
• Analysis of recrystallized Salicylic acid and Aspirin Coordinator Vipin Paliwal
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