Jun 24, 2024  
2014-2015 Undergraduate Academic Catalog 
    
2014-2015 Undergraduate Academic Catalog [ARCHIVED CATALOG]

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BE 410 - Biomaterials

3 lecture hours 0 lab hours 3 credits
Course Description
This course presents principles that apply to the selection and use of materials in medical applications. Topics covered include properties of solids, the use of phase diagrams, properties and biomedical applications of metals, properties and biomedical applications of ceramics, properties and biomedical applications of polymers, a survey of composite and textile materials, properties of living and processed tissues, wound healing, and the interaction between living tissues and artificial materials. (prereq: BI 102 , CH 222 )
Course Learning Outcomes
Upon successful completion of this course, the student will be able to:
• Describe the structure of solids as they relate to the use of engineering materials
• Describe the mechanical properties of typical engineering materials
• Interpret phase diagram and use them to understand typical material processing procedures such as heat-treatment
• Describe the typical advantages and disadvantages of metals, polymers and ceramics as biomaterials
• Describe specific advantages and disadvantages of 316L stainless steel, cobalt-chrome based alloys, titanium based alloys, polyamides, polyolefins, PVC, PMA, PMMA, hydrogels, thermal plastic polyurethane elastomers, PET, fluorocarbon polymers, silicone elastomers, alumna, silica oxide ceramics, hydroxyapatite and pyrolytic carbon as biomaterials
• Describe typical processing techniques for metals, polymers and ceramics
• Name and describe the general structure and properties of general types of biological structural materials including collagen, elastin and GAG’s
• Describe typical materials used in sutures, artificial heart valves, oxygenator membranes, TAH’s and VAD’s, pacemaker electrodes, dialyzer membranes, contact lens, implantable lens, space filling implants, orthopedic implants, bone cements and dental implants
• Describe the basic principles of tissue engineers and regenerative medicine
• Describe the processes involved in wound healing
Prerequisites by Topic
• Biochemical terminology, common proteins, common protein structures
• Introductory human biology, anatomy and physiology
• Basic atomic bonding
• Basic thermodynamic principles
• Introductory statics and strength of materials
Course Topics
• Material properties; structure of solids, mechanical properties, corrosion/degradation of materials, and material testing (5 classes)
• Metals; metallic bonding, metallic crystal structure, dislocations, strengthening mechanisms, phase diagrams, phase transformations, corrosion (3 classes)
• Ceramics; bonding and structure, degradation, fracture mechanics, piezoelectric properties, glass ceramics, apatite ceramics, carbon (2 classes)
• Polymers; polymerization process, polymer structure, viscoelastic behavior, degradation (3 classes)
• Composite and textile materials and their properties (3 classes)
• Properties and structure of tissues; collagen, elastin, calcium phosphate, composition and structure of various soft tissues, cortical and cancellous bone, and mechanical properties (3 classes)
• Principles of tissue engineering and regenerative medicine (2 classes)
• Tissue/Material Interaction; biocompatibility, surface properties, ASTM testing standards, effects of artificial materials on the body, effects of the body on artificial materials (2 classes)
Coordinator
Charles Tritt



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