Mar 14, 2025  
2023-2024 Undergraduate Academic Catalog-June Update 
    
2023-2024 Undergraduate Academic Catalog-June Update [ARCHIVED CATALOG]

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CHM 2225 - Organic Chemistry II Laboratory

0 lecture hours 4 lab hours 2 credits
Course Description
This laboratory-only course has been designed together with CHM 2210 (Organic Chemistry I) and CHM 2220 (Organic Chemistry II) to fulfill the organic chemistry requirements for admission to medical school, dental school, pharmacy school, and graduate programs. The main objective of this laboratory course is to give the students a feel for how advanced organic chemistry is carried out in practice. The experiments will employ the basic experimental practices learned during organic chemistry I, the concepts learned in organic chemistry II and are applied towards the synthesis of complex organic compounds and improving the understanding of reaction mechanisms. (prereq: none) (quarter system prereq: CH 322) (coreq: CHM 2220  or equivalent)
Course Learning Outcomes
Upon successful completion of this course, the student will be able to:
  • Conduct fractional distillation of alcohols
  • Conduct nucleophilic substitution (SN1vs SN2 reaction mechanism)
  • Conduct Infrared spectroscopy (FT-IR)
  • Conduct electrophilic aromatic substitution reaction
  • Conduct Diels-Alder reaction
  • Conduct synthesis of methyl benzoate esters
  • Conduct synthesis of aromatic carboxylic acid
  • Conduct depolymerization of plastics
  • Conduct synthesis of sulfanilamide, an amide antibiotic
  • Conduct and gain experience in complex muti-step organic synthesis

Prerequisites by Topic
  • Distillation
  • UV-Vis spectroscopy
  • Infrared spectroscopy
  • Aromatic substitution reactions
  • Dienes
  • Esters
  • Polymers
  • Amides

Laboratory Topics
  • Fractional distillation
  • UV-Vis spectroscopy and kinetics of alcohol oxidation
  • Nucleophilic substitution (SN1vs SN2 reaction mechanism)
  • Introduction to infrared spectroscopy (FT-IR)
  • Electrophilic aromatic substitution reaction
  • Dienes (Diels-Alder reaction)
  • Synthesis of methyl benzoate (ester)
  • Synthesis of p-anisic acid (aromatic carboxylic acid)
  • Depolymerization of PET plastics (synthetic polymers)
  • Synthesis of sulfanilamide (amide antibiotics synthesis)
  • Introduction to multi-step organic synthesis and product characterization

Coordinator
Dr. Vipin Paliwal



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