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Mar 13, 2025
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BME 3510 - Biotransport Phenomena4 lecture hours 0 lab hours 4 credits Course Description Thermal-fluid transport phenomena and analysis methods, as they apply to biomedical engineering problems, are covered in this course. Following a review of salient concepts in thermodynamics, the first law of thermodynamics will be used as a tool to solve steady flow device problems, including those involving psychrometric analysis for moist air applications. The mechanical energy balance and Bernoulli equations will be used to solve fluid flow problems and introduce the concept of losses. Following further introduction to fluid phenomena, including rheological properties of biological fluids, a comprehensive approach to solving fluids problems using the Navier-Stokes equations will be introduced. Principles and analysis methods to solve heat transfer and mass transfer problems will also be covered. In addition to analytic techniques, commercial finite element analysis software will be used to solve more complex biomedical transport problems using numerical techniques. (prereq: PHY 1110 ) (quarter system prereq: none) Course Learning Outcomes Upon successful completion of this course, the student will be able to:
- Determine properties of pure substances, including liquid-vapor mixtures, using property tables, phase diagrams, and software
- Apply the ideal gas equation of state to relate properties of gases and gas mixtures when appropriate
- Identify the meaning of terms in the first law of thermodynamics and apply it to analyze steady flow problems and design steady flow devices relevant to biomedical engineering
- Use psychrometric analysis to define the vapor content of atmospheric air and apply this to analysis of steady air conditioning processes
- Identify situations in which the Bernoulli equation applies and use this equation to solve practical biomedical engineering problems
- Describe common fluid rheological behaviors, including those associated with biological fluids
- Describe the significance of Reynolds number in fluid flow behavior and define laminar, turbulent and transitional flows and where they are encountered in the human body
- Explain how partial derivatives relate variables in three-dimensional flow regimes
- Use the mechanical energy balance to solve internal flow problems, including those with losses
- Set up classic and biomedical engineering problems using the continuity and Navier-Stokes equations and solve simple cases
- Define the different types of forces that fluid flow imparts on solid bodies and use correlations to estimate these forces for common geometries
- Set up classic and biomedical engineering problems using differential energy and mass balances and solve simple cases
- Apply constitutive relations related to mass diffusion and heat conduction
- Solve problems involving steady and lumped system transient conductive heat transfer
- Design heat and mass exchangers to meet specified requirements
- Describe the principles of numerical methods to solve transport problems based on partial differential equations
- Apply commercial finite element analysis software to solve biomedical engineering transport problems
- Explain the benefits and limitations of different solution approaches to biomedical engineering transport problems
Prerequisites by Topic
- Definitions of heat, internal energy, and work
- Differential calculus
Course Topics
- Review of thermodynamic definitions
- Properties of pure substances
- Application of the ideal gas equation of state
- Analysis techniques based on the first law of thermodynamics
- Gas mixtures, psychrometrics, and analysis of steady air conditioning problems
- Introduction to fluid phenomena
- Applications of the Bernoulli equation
- The mechanical energy balance, losses, and internal flow analysis
- Introduction to partial derivatives as they apply to three-dimensional flow regimes
- Continuity and Navier-Stokes equations
- External flow and drag
- Analysis of mass transfer problems using the differential component mass balance
- Transport across membranes and compartmental mass transfer analysis
- Analysis of heat transfer problems using the differential energy balance
- Heat conduction analysis for steady and lumped system transient conduction
- Heat and mass exchanger analysis and design
- Principles of numerical analysis and implementation of commercial finite element analysis software
Coordinator Dr. Charles Tritt
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