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Mar 17, 2026
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BME 4710 - Biomedical Instrumentation II2 lecture hours 3 lab hours 3 credits Course Description This course introduces the fundamentals of several biological signals, e.g., ECG, EMG, and EEG. The course also introduces electrodes and electronic amplifiers needed to acquire them. Methods for reducing electrical noise and electromagnetic interference in the signals, and conversion between analog and digital forms are included. (prereq: BME 3710 , ELE 3300 ) (quarter system prereq: BE 3705) Course Learning Outcomes Upon successful completion of this course, the student will be able to:
- Quantitatively predict electrical field distribution for simple geometries in a 3-dimensional body
- Design, construct, and test prototype circuits to detect and process electrical signals produced by the body
- Account for the electrical behavior of electrodes in recording biopotentials of human beings
- Recognize and mitigate the interference and noise in recording biological signals including the ones captured by human beings
- Convert signals between digital and analog forms
- Employ circuit simulation in the analysis and design of medical instrumentation
Prerequisites by Topic
- Use of diodes as sensor, actuator, rectifier, and regulator
- Basic electronic circuitry using operational amplifiers to amplify signals
- Effects of non-ideal operational amplifier properties on circuit performance
Course Topics
- Noise analysis
- Electromagnetic interference
- Instrumentation amplifiers
- Biopotentials and the electrical behavior of biopotential electrodes
- Voltage and current distribution in tissue from point, cylindrical, and flat surfaces
- DC offset, common mode, and high frequency interference in biopotential amplifier design and recording
- ECG design and analysis
- Analog to digital and digital to analog conversion
Laboratory Topics
- 60Hz and RF interference
- Measurements of very low impedance
- Measurements of distributed impedance
- Measurements of electrical parameters of biological media
- Temperature and flow measurements
- ECG circuit design and realization
- Software, A/D conversion and user interface of an electrocardiogram
Coordinator Dr. Icaro dos Santos
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