PER 5020 - Pathophysiology

• Explain the cellular basis of disease and the causes of cellular injury 
• Describe the vascular changes that occur with acute and chronic inflammation and list the mediators of the vascular changes 
• Describe the processes involved in tissue repair and regeneration 
• Describe the cells and mediators involved in immunity, their roles and how they are regulated 
• Describe the types of hypersensitivity reactions of the immune system and how they might develop 
• Describe the alterations that can occur in hemostasis and in delivery of blood flow, their manifestations and treatments 
• Describe the types, manifestations, and treatments of circulatory shock and coronary artery disease 
• Describe the types, manifestations, and treatments of valvular disorders, heart failure and cardiac arrhythmias 
• Describe the types, manifestations, and treatments of pericardial diseases and anemias 
• Describe the types, manifestations, and treatments of fluid and electrolyte disorders and acid/base disorders 
• Describe the types, manifestations, and treatments of intrarenal disorders and renal failure 
• Describe the types, manifestations, and treatments of respiratory disorders 
• Describe the types, manifestations, and treatments of endocrine disorders 

• Physiology of immune, cardiovascular, respiratory and renal systems

• Cell injury, aging, and death 
• Acute and chronic inflammation 
• Immune system and immune system dysfunction 
• Alterations in hemostasis and hemodynamic disorders 
• Circulatory shock  
• Coronary artery disease and coronary catheterization  
• Valvular heart disease and heart failure 
• Hypertension and cardiac arrythmias 
• Pericardial disease, anemias and transfusions 
• Fluid and electrolyte disorders and acid/base disorders 
• Intrarenal disorders 
• Renal failure 
• Respiratory disorders 
• Endocrine disorders