Apr 19, 2024  
2023-2024 Graduate Academic Catalog 
    
2023-2024 Graduate Academic Catalog [ARCHIVED CATALOG]

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PER 5010 - Advanced Physiology

4 lecture hours 0 lab hours 4 credits
Course Description
This course presents the concepts of human physiology that are most pertinent to the field of perfusion. These include homeostasis, cell structure and function, genetics, cellular energy production, macromolecules, cell membrane potentials and transport mechanisms, smooth and skeletal muscle structures and functions, and the structures and functions of the following: cardiovascular system, endocrine system, autonomic nervous system, respiratory system, and renal system. (prereq: none)
Course Learning Outcomes
Upon successful completion of this course, the student will be able to:
  • Apply the concept of homeostasis to the control select regulated variables  
  • Identify the structures common to eukaryotic cells and explain how each contributes to functions of various cell types. Predict how cell structures would vary between cell types
  • Contrast the pathways by which charged and uncharged molecules can traverse the plasma membrane and identify the factors that would impact the rate of molecular movement in these pathways  
  • Explain how membrane potentials are generated and predict the changes that will occur in membrane potentials when ion concentration or permeabilities change 
  • Identify the structures of the heart 
  • Name and identify the locations of the major blood vessels 
  • Explain the physical principles and physiological processes that regulate function of the cardiovascular system 
  • Describe the steps of hemostasis, including the specific roles of platelets and clotting factors 
  • Describe the components of the immune system and how they interact to functionally provide immune function 
  • Discuss the roles of the autonomic nervous system and endocrine system in homeostatic feedback loops 
  • Describe the body compartments, their relative sizes and identify how water moves between the compartments 
  • Describe the anatomy and physiology of the urinary system, including the regulation of GFR, functional aspects of the nephron and control of secretion and reabsorption that occurs along the nephron 
  • Discuss the mechanisms of acid/base balance and apply them to physiological situations 
  • Describe the anatomy and physiology of the respiratory system, including mechanisms for gas exchange and transport 
  • Describe the major functions of the liver 

Prerequisites by Topic
  • Macromolecules and their functions 
  • Cell structures and functions 

Course Topics
  • Homeostasis and cell function  
  • Cell membrane and transport mechanisms 
  • Genetics 
  • Electrophysiology 
  • Skeletal and smooth muscle structure and function  
  • Cardiovascular anatomy and physiology 
  • Hemostasis 
  • Immunity  
  • Autonomic nervous system  
  • Endocrine system  
  • Body fluid compartments  
  • Urinary system  
  • Acid/base balance  
  • Respiratory system  
  • Liver 

Coordinator
Dr. Ron Gerrits



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