Dec 01, 2023  
2021-2022 Undergraduate Academic Catalog 
2021-2022 Undergraduate Academic Catalog [ARCHIVED CATALOG]

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BE 410 - Biomaterials

3 lecture hours 0 lab hours 3 credits
Course Description
This course presents principles related to the selection and use of biomaterials. Topics covered include the general properties and behavior of materials, the use of phase diagrams, the use of Pourbaix diagrams, properties and biomedical applications of particular metals, properties and biomedical applications of particular ceramics, properties and biomedical applications of particular polymers, a survey of composite and textile materials, wound healing, and the interaction between living tissues and artificial materials. (prereq: BI 102 , CH 222 , ME 207 )
Course Learning Outcomes
Upon successful completion of this course, the student will be able to:
  • Describe the structure of solids as they relate to the use of engineering materials
  • Describe the mechanical properties of typical engineering materials
  • Interpret phase diagrams and use them to understand typical material processing procedures such as heat-treatment
  • Describe the typical advantages and disadvantages of metals, polymers, and ceramics as biomaterials
  • Solve biomedical engineering problems related to selection and processing of metallic, polymeric, and ceramic biomaterials
  • Describe specific advantages and disadvantages of a variety of common biomaterials
  • Describe typical corrosion and fatigue processes and evaluate the expected corrosion and fatigue response to typical biomaterials.
  • Describe and solve engineering problems related to typical processing techniques for metals, polymers, and ceramics
  • Describe some typical materials used in sutures, artificial heart valves, oxygenator membranes, TAHs and VADs, pacemaker electrodes, dialyzer membranes, contact lens, implantable lens, space filling implants, orthopedic implants, bone cements, and dental implants
  • Consider, evaluate and discuss the global, economic, environmental, and societal impacts of the use of particular biomaterials
  • Independently investigate the professional literature regarding a timely biomaterials topic and present findings

Prerequisites by Topic
  • Biochemical terminology, common proteins, common protein structures
  • Basic atomic bonding
  • Basic thermodynamic principles
  • Introductory statics and strength of materials

Course Topics
  • Material properties: structure of solids, mechanical properties, corrosion/degradation of materials, and material testing
  • Phase diagrams as they relate to biomaterials
  • Metals: metallic bonding, metallic crystal structure, dislocations, strengthening mechanisms, phase diagrams, phase transformations, corrosion
  • Ceramics: bonding and structure, degradation, fracture mechanics, piezoelectric properties, glass ceramics, apatite ceramics, carbon
  • Polymers: polymerization process, polymer structure, viscoelastic behavior, degradation
  • Composite and textile materials and their properties
  • Tissue/material interaction; biocompatibility, surface properties, ASTM testing standards, effects of artificial materials on the body, effects of the body on artificial materials
  • Student presentations

Dr. Charles S. Tritt

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