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Apr 19, 2024
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CH 223 - Biochemistry3 lecture hours 2 lab hours 4 credits
Course Description
This course is designed to train and educate students with essential and central concepts, principles and applications of biochemistry. Knowledge of biochemistry is essential in disciplines like medicine, nutrition, pharmacology, bioremediation studies, and agriculture and in several engineering fields. The three-dimensional structures of biomolecules are explored in the context of their functions and their microenvironments within living organisms and metabolism is introduced. The course enhances the ability of students to address changes, needs and demands of their own major fields as well. The lab-activity allows hands on experience on concepts taught in lecture. (prereq: CH 222 )
Course Learning Outcomes
Upon successful completion of this course, the student will be able to:
- Identify and name different types of biomolecules, DNA, RNA, proteins, lipids, carbohydrates, etc.
- Understand the structures and functions of the biomolecules, DNA, RNA, proteins, lipids and establish the structure-function relationship for the different biomolecules
- Manipulate basic structural and functional concepts about biomolecules and biopolymers like nucleic acids, carbohydrates, proteins, enzymes and lipids
- Translate the genetic code and understand the importance of single, double or multiple mutations in a genome
- Analyze and apply the interrelationship of biochemistry reactions with those of the human body and metabolic processes essential to body functions
- Participate in scientific conversations about biochemistry, using correct terminology, ask relevant questions in a seminar or colloquium with confidence and take part in science activities (presentations and meetings) individually or as a team member
- Use proper and accurate basic biochemistry laboratory techniques and handle the biochemicals appropriately under a variety of circumstances
- Handle and dispose all biochemical materials safely
Prerequisites by Topic
- Positive and negative ions
- Amines
- Amides
- Carboxylic acids
- Acid derivatives
- Nucleophiles
- Electrophiles
Course Topics
- Proteins-structures, assembly, functions and applications (6 classes)
- Enzymes-structures and functions (2 classes)
- Nucleic acids-structures, functions, and applications (4 classes)
- Genetic code, translation, gene expression (4 classes)
- Carbohydrates-structures, functions and roles in metabolism (2 classes)
- Lipids, steroids and hormones (2 classes)
- Biochemistry leading to biotechnology (1 class)
- Biochemistry seminar by guest speaker (1 class)
Laboratory Topics
- Introduction to the properties of proteins
- Introduction to carbohydrates and their qualitative analysis
- Introduction to the properties of lipids
- Modeling the nucleic acids: nonbonding interaction
- Modeling the nucleic acids: replication and transcription
- Modeling the nucleic acids: translation and mutation
- Blood typing HIV (simulating) test
- Chromatography of amino acids
- Sugars
Coordinator
Dr. Gul Afshan
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