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Apr 23, 2024
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PE 673 - Advanced Physiology I3 lecture hours 0 lab hours 3 credits Course Description This course is designed to cover the anatomy and physiology of select body systems. Areas covered include cell structure and function (with an emphasis on membrane function and transporters), membrane potentials and action potentials, skeletal and smooth muscle structure and function, and cardiovascular structure and function. (prereq: at least one previous course in physiology or anatomy and physiology) Course Learning Outcomes Upon successful completion of this course, the student will be able to:
- Explain the structural and functional properties of eukaryotic cells, and how gene expression affects these properties
- Explain the importance of movement of molecules across the cell membrane, the pathways for this movement and the factors that affect movement of these molecules
- Explain how membrane potentials are generated and predict the changes that will occur in membrane potentials when ion concentration or permeabilities change
- Identify the structures of the heart and name the major blood vessels
- Explain the physical principles and physiological processes that regulate function of the cardiovascular system
- Identify the waves of an EKG and explain what each wave represents
- Explain the feedback loops that are active in the control of arterial pressure
- Describe the steps involved in hemostasis, including the specific roles of platelets and clotting factors
Prerequisites by Topic
- Undergraduate exposure to all topics
Course Topics
- Homeostasis and cell function (1.5 class periods)
- Cell membrane and transport mechanisms and genetics (1.5 class periods)
- Electrophysiology (3 class periods)
- Skeletal muscle structure and function (1.5 class periods)
- Smooth muscle structure and function (1.5 class periods)
- Heart anatomy and muscle function (1.5 class periods)
- Cardiac channels, pumps and exchangers (1.5 class periods)
- Rhythmical excitation of the heart (1.5 class periods)
- EKG (1.5 class period)
- Anatomy and physics of the circulation (3 class periods)
- Vascular distensibility (1.5 class periods)
- Microcirculation and lymphatics (1.5 class periods)
- Local and nervous control of blood flow (1.5 class periods)
- Long-term regulation of arterial pressure (1.5 class periods)
- Hemostasis (1.5 class period)
- Exams (4 class periods)
Coordinator Dr. Ronald Gerrits
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