PE 675 - Pathophysiology

• Explain the cellular basis of disease and the causes of cellular injury
• Describe the vascular changes that occur with acute and chronic inflammation and list the mediators of the vascular changes
• Describe the processes involved in tissue repair and regeneration
• Describe the cells and mediators involved in immunity, their roles and how they are regulated
• Describe the types of hypersensitivity reactions of the immune system and how they might develop
• Describe the alterations that can occur in hemostasis and in delivery of blood flow, their manifestations and treatments
• Describe the types, manifestations and treatments of circulatory shock and coronary artery disease
• Describe the types, manifestations and treatments of valvular disorders, heart failure and cardiac arrhythmias
• Describe the types, manifestations and treatments of pericardial diseases and anemias
• Describe the types, manifestations and treatments of fluid and electrolyte disorders and acid/base disorders
• Describe the types, manifestations and treatments of intrarenal disorders and renal failure
• Describes the types, manifestations and treatments of respiratory disorders
• Describe the types, manifestations and treatments of endocrine disorders

• An understanding of anatomy and physiology of the systems covered

• Cell injury, aging and death (1 class)
• Acute and chronic inflammation (1 class)
• Immune system and immune system dysfunction (2 classes)
• Alterations in hemostasis and hemodynamic disorders (1 class) • Circulatory shock (1 class)
• Coronary artery disease and coronary catheterization (1 class)
• Valvular heart disease and heart failure (1 class)
• Hypertension and cardiac arrythmias (1 class)
• Pericardial disease, anemias and transfusions (1 class)
• Fluid and electrolyte disorders and acid/base disorders (1 class)
• Intrarenal disorders (1 class)
• Renal failure (1 class)
• Respiratory disorders (1.5 classes)
• Endocrine disorders (1.5 classes)
• Exams (3 classes)