PE 673 - Advanced Physiology I

• Explain the structural and functional properties of eukaryotic cells, and how gene expression affects these properties
• Explain the importance of movement of molecules across the cell membrane, the pathways for this movement and the factors that affect movement of these molecules
• Explain how membrane potentials are generated and predict the changes that will occur in membrane potentials when ion concentration or permeabilities change
• Identify the structures of the heart and name the major blood vessels
• Explain the physical principles and physiological processes that regulate function of the cardiovascular system
• Identify the waves of an EKG and explain what each wave represents
• Explain the feedback loops that are active in the control of arterial pressure
• Describe the steps involved in hemostasis, including the specific roles of platelets and clotting factors

• Undergraduate exposure to all topics

• Homeostasis and cell function (1.5 class periods)
• Cell membrane and transport mechanisms and genetics (1.5 class periods)
• Electrophysiology (3 class periods)
• Skeletal muscle structure and function (1.5 class periods)
• Smooth muscle structure and function (1.5 class periods)
• Heart anatomy and muscle function (1.5 class periods)
• Cardiac channels, pumps and exchangers (1.5 class periods)
• Rhythmical excitation of the heart (1.5 class periods)
• EKG (1.5 class period)
• Anatomy and physics of the circulation (3 class periods)
• Vascular distensibility (1.5 class periods)
• Microcirculation and lymphatics (1.5 class periods) 
• Local and nervous control of blood flow (1.5 class periods)
• Long-term regulation of arterial pressure (1.5 class periods) 
• Hemostasis (1.5 class period)
• Exams (4 class periods)