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Dec 04, 2024
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BE 3100 - Quantitative Systems Physiology I3 lecture hours 0 lab hours 3 credits Course Description The objective of this course is to present the concepts of human physiology that are most pertinent to the field of biomedical engineering. Concepts from the following topics will be covered: homeostasis, cell membrane potentials and transport mechanisms, nerve and muscle, and heart and the circulatory system. (prereq: BI 102 ) Course Learning Outcomes Upon successful completion of this course, the student will be able to: • explain the concept of homeostasis, describe the components of a negative feedback loop
• describe the types of channels, transporters and exchangers that are used to move molecules across membranes
• explain the importance of membrane potentials, write the electrical analog equation for calculating membrane voltage and use this equation to predict changes in membrane voltage when provided with changes to ion concentrations or membrane conductance
• explain how cells communicate using electrical and chemical transmission techniques
• describe the general organization of the nervous system, including the ANS and its divisions
• identify the main functions of select brain regions
• explain the role of the nervous system in homeostatic feedback loops
• discuss the ways that information can be coded within neural circuits
• compare and contrast skeletal and smooth muscle function and regulation
• explain/analyze the length-tension curves of muscles
• describe the anatomical features of the cardiovascular system and explain how these features correlate with function
• use PV loops to describe and analyze cardiac function
• use feedback loops to describe the regulation of blood pressure and blood flow
• Interpret a standard ECG tracing Prerequisites by Topic • Cell biology Course Topics • Functional organization of the human body (l class)
• Homeostasis, the cell and its function (1 class)
• Diffusion, osmosis and ion transport (2 classes)
• Membrane and action potentials (3 classes)
• Nervous system (4 classes)
• Skeletal muscle contraction and excitation (4 classes)
• Smooth muscle contraction and excitation (1 classes)
• Heart muscle and function (3 classes)
• EKG and cardiac abnormalities (2 classes)
• Circulation and hemodynamics (5 classes)
• Exams (3 classes) Coordinator Ronald Gerrits
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