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Mar 14, 2026
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BME 5210 - Medical Imaging Systems3 lecture hours 2 lab hours 4 credits Course Description This course introduces medical imaging modalities and the foundations of image processing. Core concepts in physics, technology, and operation are covered for x-ray radiography, computed tomography, magnetic resonance imaging, and ultrasound. Image acquisition, reconstruction techniques, and classical processing methods establish the foundational knowledge required for medical imaging analysis. Students apply these concepts through hands-on laboratory projects in image acquisition, processing, and 3D printing using real and simulated datasets. The course extends to AI-enabled image processing, where students develop foundational knowledge of deep learning architectures as applied to tasks such as image reconstruction, data augmentation, image segmentation, and classification. Through project-based learning, students implement and critically evaluate AI-enabled image processing workflows and output for clinical relevance, accuracy, and performance limitations. Graduate students prepare critical summaries of published research in AI, machine learning, or data science applied to medical imaging. Summaries are refined through iterative faculty feedback and culminate in formal class presentations. Prereq: CSC 4611 or ELE 3300 or CSC 5611 or CSC 5616 or CSC 6621 Note: This course is open to qualified undergraduate students. Course Learning Outcomes Upon successful completion of this course, the student will be able to:
- Demonstrate an understanding of fundamental multi-dimensional systems and signals concepts
- Demonstrate an understanding of general image characteristics across various imaging modalities
- Demonstrate an understanding of physics fundamentals of various imaging modalities
- Demonstrate an understanding of how a basic x-ray radiography system works, and how images are created and analyzed
- Demonstrate an understanding of how a basic CT system works, and how images are created and analyzed
- Demonstrate an understanding of how a basic MRI system works, and how images are created and analyzed
- Demonstrate an understanding of how a basic ultrasound system works, and how images are created and analyzed
- Demonstrate an understanding of how basic nuclear medicine systems (e.g., PET and SPECT) work, and how images are created and analyzed.
- Demonstrate an understanding of fundamental image processing methodologies
- Proficiently apply fundamental image processing methodologies to medical images
- Proficiently apply MATLAB and Anatomage Table (or other modern computer-aided tools) to perform image analysis and visualization
- Critically evaluate published research in AI, machine learning, or data science applied to medical imaging, and communicate findings through written summaries and formal oral presentations
- Explain the foundational concepts of deep learning and convolutional neural network (CNN) architectures, as they apply to medical image analysis
- Select appropriate AI-enabled models for medical imaging tasks based on the characteristics of the imaging dataset and the intended application
- Implement AI-enabled image processing models on medical imaging datasets and document relevant model parameters, training configurations, and output metrics for quantitative performance assessment
- Evaluate the performance of AI models applied to medical images using appropriate metrics, and interpret results in terms of model accuracy, limitations, and fitness for a specific clinical application
- Assess the trustworthiness of AI-enabled medical imaging solutions by examining model explainability, transparency of decision-making, potential sources of bias, and the broader implications for clinical reliability and patient safety
Prerequisites by Topic
- Linear and time-invariant systems
- Signal transformations
- Impulse response function and convolution
- Medical imaging phantom design
Course Topics
- Introduction to medical imaging systems and their development
- Fundamentals of multi-dimensional systems and signals
- Image characteristics and medical imaging data standards (DICOM and NIfTI)
- Fundamentals of image processing
- Medical imaging phantoms and their role in system evaluation
- X-ray radiography and angiography systems
- Computed tomography (CT) systems
- Magnetic resonance imaging (MRI) systems
- Ultrasound imaging systems
- Deep learning fundamentals
- AI-enabled applications in medical imaging
Laboratory Topics
- Medical image visualization, display, and quantification
- Image processing and spatial-frequency analysis
- Image reconstruction and acquisition, including optical CT systems
- Image classification and segmentation
- AI-enabled medical image analysis and deep learning applications
- Phantom design, fabrication, and imaging-based quantification
Coordinator Dr. Olga Imas
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