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CHM 1250 - Chemistry for the Life Sciences II3 lecture hours 2 lab hours 4 credits
Course Description
This is a survey course for healthcare professionals introducing the fundamental concepts of organic chemistry and biochemistry and is a continuation of Chemistry for Life Sciences I. Students will gain knowledge of concepts and perform hands-on laboratory experiments. Students will be introduced to functional group structures and reactions of hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids, esters, amines, and amides. Students will learn about the structure and function of biomolecules, including enzymes and vitamins, carbohydrates, lipids, amino acids and proteins, and nucleic acids. Metabolism and energy production from carbohydrates, lipids, and proteins will be studied. The biochemical basis of medical conditions such as diabetes and ketoacidosis will be discussed.
Prereq: CHM 1050
Note: This course is not open to engineering students.
This course meets the following Raider Core CLO Requirement: None
Course Learning Outcomes
Upon successful completion of this course, the student will be able to:
- Name and draw structural formulas of organic compounds and describe bonding conformation, and isomerism for organic functional groups including aromatic compounds, alkanes, alkenes, alkynes, amines, alcohols, thiols, ethers, aldehydes, esters, ketones, carboxylic acids and amides
- Recognize functional groups and reactions between organic molecules and between functional groups in biological molecules and medicinal compounds
- Explain physical and chemical properties of functional groups using molecular properties and structure
- Describe structure, chemical properties, and structure-function relationships in proteins, carbohydrates, lipids and nucleic acids.
- Identify nucleotides and nucleosides, describe structure of DNA, outline replication process, describe transcription and translation, explain how genetic code functions, describe mutations
- Describe nutritional requirements, vitamins and minerals
- Describe chemical and energetic changes during the stages of metabolism for carbohydrates, fats and proteins and their links to some diseases
Prerequisites by Topic
- Atomic structure
- Chemical bonding
- Molecular geometry
- Electronegativity
- Bond and molecular polarity
- Intermolecular forces
Course Topics
- Aromatic compounds
- Functional groups- alkanes, alkenes, alkynes, aromatic compounds, alcohols, aldehydes and ketones, carboxylic acids, esters, amines, and amides
- Chiral molecules, Fischer and Haworth structures
- Carbohydrate structure and function
- Protein structure and function
- Enzyme and vitamins
- Lipid structure and function
- DNA and RNA structure and function
- Mutations and human genetic diseases
- Human nutritional requirements
- Glucose and glycogen metabolism
- Lipid metabolism and ketone bodies
- Protein catabolism and fate of 20 amino acids
Laboratory Topics
- Organic chemistry techniques
- Reactions of hydrocarbons
- Alcohols and phenols
- Aldehydes and ketones
- Carboxylic acids and esters
- Aspirin synthesis, testing aspirin products
- Saponification and soaps
- Properties of vitamins
- Chemistry of amino acids
- Peptides and proteins
- Tests for carbohydrates
- Tests for lipids
- Enzymes
- Modeling of DNA components and extraction of DNA
- Kidney function tests
- LDH as disease marker
- Biochemical analysis of normal and pathological urine
Coordinator
Dr. Anne-Marie Nickel
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