Apr 03, 2026  
2025-2026 Undergraduate Academic Catalog 
    
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2025-2026 Undergraduate Academic Catalog [ARCHIVED CATALOG]

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CBE 3300 - Bioinformatics

3 lecture hours 2 lab hours 4 credits
Course Description
This course will introduce Chemical and Biomolecular Engineering students to bioinformatics and its ever-increasing power in solving various complex problems in medicine and drug development. 1) Students will explore in detail the building blocks of biomolecules and their physicochemical properties to lay the foundation for better understanding the constantly “breathing” biomolecules and their delicate - intramolecular and intermolecular - interactions with their working partners in action. 2) Students will learn how to navigate the human genome as well as its organization and dynamics, determine any given gene’s exact chromosomal location, and explore the gene. 3) Students will learn how to search against a wide array of specialized bioinformatics databases and retrieve their desired information effectively and efficiently. 4) Students will learn various sequence alignment algorithms in use today and practice them in processing of biosequences.
Prereq: (prereq: BIE/CBE 2300 , CHM 2310 ) (quarter system prereq: CH 223, EB 2420, EB 2430)
Note: None
This course meets the following Raider Core CLO Requirement: Integrate Learning
Course Learning Outcomes
Upon successful completion of this course, the student will be able to:
  • Acknowledge the ever-increasing power of bioinformatics
  • Apply the physicochemical properties to understand biomolecular structures
  • Navigate the human genome browser to determine the exact chromosomal location of a gene
  • Understand search algorithms to search for similar biosequences
  • Search a query against various specialized bioinformatics databases
  • Unambiguously differentiate similarity and homology of biosequences
  • Understand various biosequence alignment algorithms
  • Understand the fundamental concept of comparative sequence analysis
Prerequisites by Topic
  • None
Course Topics
  • Introduction to bioinformatics
  • Bioinformatics of nucleic acids
  • Bioinformatics of proteins
  • Browsing genomes and their data
  • Sequence similarity search
  • Bioinformatics databases
  • Human genome organization and dynamics
  • Sequence alignment algorithms
Laboratory Topics
  • Introduction lab
  • Understanding nucleic acid structure and function
  • Understanding protein structure and function
  • Browsing genomes and genes
  • Searching various NCBI Entrez databases
  • BLAST similarity search
Coordinator
Dr. Jung Lee


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