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NUR 2001 - Pathophysiology and Pharmacology I5 lecture hours 0 lab hours 5 credits Course Description This course is the first in a two-part series to provide students with an understanding of disease process including etiology, manifestations, diagnosis, and treatment modalities. The course aligns understanding of the effects of drugs on the physiological systems. Central concepts of pathophysiology and homeostasis provide the foundation for understanding alterations in cellular, hematopoietic, cardiovascular, respiratory, and endocrine functions, fluid and electrolyte balance, acid-base balance, and genetics. Central concepts in pharmacology provide the foundation for understanding specific drug mechanisms of action, safe administration and monitoring for potential adverse effects, drug interactions, evaluation, and drug-related patient education. Drugs affecting the autonomic nervous, immune, cardiovascular, respiratory, endocrine, and hematopoietic systems, and coagulation pathways, fluid and electrolyte balance, and cancer treatment are discussed. Prereq: BIO 1410 (C grade), BIO 1420 (C grade) (quarter system prereq: BI 2040 and MA 1204 or MA 125) Coreq: MTH 1030 Note: None This course meets the following Raider Core CLO Requirement: None Course Learning Outcomes Upon successful completion of this course, the student will be able to:
- Use clinical judgment and an understanding of the pathogenesis, compensatory mechanisms, clinical manifestations, diagnostic tests, treatment modalities and disease sequelae to identify nursing interventions that address disease processes (Person-Centered Care; Clinical Judgment)
- Incorporate knowledge of the basic principles of pharmacodynamics and pharmacokinetics to explain the concepts of drug mechanism of action; timing of medication; drug reactions; and potential interactions (Evidence-Based Practice)
- Apply core drug knowledge, clinical judgment, and effective communication skills in conjunction with the nursing process to describe safe administration of medications, prevention, detection, and response to adverse drug effects, evaluation of effectiveness of drug therapy, and patient education (Person-Centered Care; Clinical Judgment; Communication)
- Explain the role of genetic factors in drug selection, drug metabolism, and triggering disease processes (Evidence-Based Practice)
- Accept personal responsibility and participate in own development toward the role of the professional nurse through acts of integrity, mutual respect, and actively seeking out opportunities to learn (Professional Role)
- Acknowledge the importance of accessing current and reliable sources to maintain and update one’s knowledge of disease conditions and drugs over the course of a nursing career (Evidence-Based Practice)
Prerequisites by Topic Course Topics
- Pathophysiology:
- Cellular responses to stress, injury, and aging
- Inflammation, tissue repair and fever, cell proliferation and tissue regeneration
- Genetic control of cell function, inheritance, and genetic and congenital disorders
- Neoplasia
- Disorders of fluid, electrolyte, and acid/base balance
- Disorders of the white blood cells and lymphoid tissue
- Mechanisms of infectious disease and innate and adaptive immunity
- Disorders of the immune system
- Disorders of hemostasis
- Disorders of red blood cells
- Disorders of endocrine function, diabetes mellitus, and metabolic syndrome
- Control of cardiovascular function, disorders of blood flow and blood pressure, and cardiac function, including heart failure and circulatory shock
- Control of respiratory function, respiratory tract infections, neoplasms, childhood disorders and disorders of ventilation and gas exchange
- Pharmacology:
- Pharmacology and the nursing process
- Pharmacokinetics and pharmacodynamics
- Adverse drug reactions and food and drug Interactions
- Immunizations, immunosuppressants and glucocorticoid drugs
- Adrenergic agonist and blocker drugs, cholinergic agonist and blocker drugs, and cholinesterase inhibitor drugs
- Muscle relaxants and anesthesia drugs
- Endocrine drugs
- Drugs affecting fluid and electrolyte balance
- Drugs to treat hypertension, congestive heart failure, angina pectoris, myocardial infarction, and dyslipidemias
- Anti-coagulants and drugs for anemias and hematopoietic drugs
- Cancer chemotherapy
- Respiratory drugs
Coordinator Dr. Stephanie Bruce
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