Mar 20, 2023  
2015-2016 Undergraduate Academic Catalog 
2015-2016 Undergraduate Academic Catalog [ARCHIVED CATALOG]

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BE 3600 - Biomedical Instrumentation

3 lecture hours 3 lab hours 4 credits
Course Description
This course focuses on the fundamental devices, circuitry and techniques needed to acquire and process biomedical quantities and signals. The application of displacement, force and pressure transducers in the conversion of physical quantities to electrical signals is discussed. Operational amplifiers are introduced and used in amplifier and filter circuits to process the signals. Non-ideal op amp properties, including finite gain, frequency response, stability, input and output resistances, bias currents and offset voltages, are treated in sufficient depth to permit design of high gain circuits capable of handling small DC and low frequency AC voltages. Transmission of physical variables through a medium to a sensor is treated in the case of an indwelling arterial catheter and pressure transducer. (prereq: BE 206  or EE 3002B )
Course Learning Outcomes
Upon successful completion of this course, the student will be able to:
  • Utilize transducers in the measurement of physiological signals of medical interest
  • Design basic electronic circuitry using operational amplifiers to amplify the signals produced by resistive pressure, flow and displacement transducers
  • Predict and test the dynamic performance of fluid systems used for blood pressure measurement
  • Design basic passive filters and 2nd order active filters to process signals
  • Predict the overall performance of cascaded processing modules
  • Design circuitry to generate periodic voltage or current waveforms
  • Assess the stability of feedback systems with respect to oscillation
  • Assess the effect of non-ideal operational amplifier properties on circuit performance
  • Use circuit simulation programs to design and test circuits and model fluid systems

Prerequisites by Topic
  • AC, DC, and transient circuit analysis in the time domain
  • AC, DC, and transient circuit simulation using Pspice or Multisim
  • Laplace circuit analysis
  • Bode plots
  • Ability to conduct laboratory experiments using function generators, power supplies, multi-meters and oscilloscopes

Course Topics
  • Amplification concepts using simple 3-element models: cascading and loading effects
  • Amplifier implementation using operational amplifiers: inverting, non-inverting, summing amplifiers
  • Difference amplifiers and fundamentals of instrumentation amplifiers
  • Linear and angular displacement transducers and blood pressure transducers
  • First and second order filters implemented with op amps, low pass, high pass and band pass
  • Analysis of fluid system based on a blood pressure transducer and catheter tubing
  • Static non-ideal op amp characteristics: offset voltages and bias currents, finite gain and input and output resistances
  • Dynamic non-ideal op amp characteristics: finite bandwidth, frequency response and slew rate
  • Stability of feedback amplifiers
  • Positive feedback, hysteresis, and relaxation oscillators

Laboratory Topics
  • Introduction to amplifier concepts using dependent sources and a circuit simulation program
  • Design and implementation of basic amplifiers using op amps
  • Electrical measurement of angles; goniometer simulation
  • Design and implementation of a blood pressure transducer amplifier using an instrumentation amplifier
  • Filtering an ECG waveform containing typical interference found in the laboratory setting (2wks)
  • Dynamic analysis and testing of a blood pressure transducer and tubing system (2wks)
  • Investigation of non-ideal operational amplifier characteristics
  • Linear, sinusoidal oscillator or relaxation oscillator design and implementation

Aaron Suminski

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