Sep 28, 2024  
2015-2016 Undergraduate Academic Catalog 
    
2015-2016 Undergraduate Academic Catalog [ARCHIVED CATALOG]

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CH 2251 - Organic Chemistry for Life Sciences

3 lecture hours 2 lab hours 4 credits
Course Description
The course concisely focuses on what students need to know in order to continue with biochemistry in the next quarter. Basic nomenclature rules will be introduced. Important functional groups involved in biological molecules will be studied. This includes alcohols, amines, amides, aldehydes and ketones, carboxylic acids and their derivatives. Further, this course also introduces students to biomolecules, proteins, carbohydrates, lipids, and nucleic acids in preparation for the Biochemistry course. Correlations will be made with important biomolecules such that students benefit in other courses such as Pharmacology and Physiology.  (prereq: CH 2050 )
Course Learning Outcomes
Upon successful completion of this course, the student will be able to:
  • Upon successful completion of this course, the student will:
  • Name and draw structural formulas of organic compounds, describe bonding and isomerism, identify functional groups, conformations, properties of alkanes, alkenes, alkynes
  • Describe aromatic compounds and benzene structure, properties and uses
  • Classify alcohols, phenols, thiols and ethers, identify alcohol groups biological molecules  describe hydrogen bonding, chemical properties of alcohols
  • Describe physical and chemical properties of aldehydes and ketones, industrial and biologically important aldehydes and ketones
  • Describe physical and chemical properties of carboxylic acids and esters
  • Classify amines and assign names, recognize key reactions, names amines as neurotransmitters, give uses of specific biological amines like epinephrine, amphetamines and alkaloids
  • Name amides, show hydrogen bonding, give products of acid and base hydrolysis, make connection with biological amides in peptides and proteins
  • Understand protein chemistry: identify structure of 20 amino acids, organic chemistry of peptide bond formation,  describe proteins in terms of size, fibrous, globular, structural hierarchy, explain hydrolysis & denaturation
  • Understand carbohydrate chemistry: structure of monosaccharides, Fischer & Haworth structures, structure and chemical properties, di and polysaccharides, describe stereoisomerism, write organic reactions of oxidation, reduction and glycoside bond formation
  • Understand lipid chemistry: classify lipids, draw structures of fats and oils, describe their chemical properties, describe phosphoglycerides, sphingolipids, describe major features of sphingolipids, identify steroids
  • Understand nucleic acid chemistry: identify structures of nucleotides and nucleosides describe structure of DNA, RNA, AMP, ADP, ATP
  • Organic and inorganic compounds comparison, Nomenclature of alkanes, alkenes and alkynes, isomerism, conformations, physical and chemical properties, polymers of alkenes
  • Aromatic compounds, benzene derivatives,  properties and uses
  • Naming and classifying alcohols, physical properties, reactions of alcohols. phenols, ether, thiol their biochemical importance, ether anesthetics
  • Naming aldehydes and ketones, physical properties, chemical properties: oxidation, hydrogenation, hemi-actal. Important aldehydes and ketones, chiral molecules, fischer projections
  • Naming carboxylic acids and esters, physical properties, reactions of carboxylic acids and esters, alph hydroxacids
  • Naming amine and amides, physical and chemical properties, biological important amines
  • Protein chemistry: alpha amino acids, reactions of peptide bond formation, size, function, fibrous, globular, structural hierarchy of proteins, hydrolysis & denaturation of proteins
  • Carbohydrate chemistry: types of carbohydrates, Fischer & Haworth structures, structure and chemical properties, di and polysaccharides, describe stereoisomerism, write reactions of oxidation, reduction and glycoside bond formation
  • Lipid chemistry: classification of lipids, structures of fats and oils, describe their chemical properties, describe phosphoglycerides, sphingolipids, describe major features of sphingolipids, identify steroids
  • Understand nucleic acid chemistry: identify structures of nucleotides and nucleosides describe structure of DNA, RNA, AMP, ADP, ATP

Prerequisites by Topic
  • None

Course Topics
  • Organic and inorganic compounds comparison, Nomenclature of alkanes, alkenes and alkynes, isomerism, conformations, physical and chemical properties, polymers of alkenes
  • Aromatic compounds, benzene derivatives,  properties and uses
  • Naming and classifying alcohols, physical properties, reactions of alcohols. phenols, ether, thiol their biochemical importance, ether anesthetics
  • Naming aldehydes and ketones, physical properties, chemical properties: oxidation, hydrogenation, hemi-actal. Important aldehydes and ketones, chiral molecules, fischer projections
  • Naming carboxylic acids and esters, physical properties, reactions of carboxylic acids and esters, alph hydroxacids
  • Naming amine and amides, physical and chemical properties, biological important amines
  • Protein chemistry: alpha amino acids, reactions of peptide bond formation, size, function, fibrous, globular, structural hierarchy of proteins, hydrolysis & denaturation of proteins
  • Carbohydrate chemistry: types of carbohydrates, Fischer & Haworth structures, structure and chemical properties, di and polysaccharides, describe stereoisomerism, write reactions of oxidation, reduction and glycoside bond formation
  • Lipid chemistry: classification of lipids, structures of fats and oils, describe their chemical properties, des
  • Nucleic acid chemistry: nucleotides, nucleosides, structures of DNA, RNA, AMP, ADP, ATPcribe phosphoglycerides, sphingolipids, describe major features of sphingolipids, identify steroids

Laboratory Topics
  • Introduction to Organic chemistry techniques (Handout)
  • Reactions of hydrocarbons (pg.241)
  • Alcohols and Phenols (pg. 253)
  • Aldehydes and Ketones (pg. 265)
  • Carboxylic acids and estes (pg. 289)
  • Aspirin synthesis (pg. 303)
  • Testing aspirin products (pg. 309)
  • Saponification and soaps (pg. 345)

Coordinator
Vipin Paliwal



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