ME 581 - Aerodynamics

• Have a thorough understanding of fluid flows over bluff and streamlined bodies, including potential flow results, circulation, boundary layers, transition, and experimental results
• Choose an airfoil and apply lift, drag, and moment coefficients to a design, and to be able to measure these coefficients experimentally |Be able to make thin airfoil and finite airfoil calculations
• Make airplane stability and trim calculations
• Have an introduction to automobile aerodynamics

• Incompressible flow, Bernoulli equation
• Laminar and turbulent flows, Reynolds number, viscosity
• Boundary layers
• Integral calculus

• Review of fluids, non-dimensionalization, boundary layer, friction
• 2-D flow over cylinders and airfoils
• Movies and laboratory experiments
• Airfoil terminology, characteristics, and physical flow description, modern airfoil developments, high lift devices
• Thin airfoil theory
• Finite airfoil
• Stability and control
• Propellers, vortex motion, model airplanes
• Automotive applications
• Graduate Students will be given additional assignments

• Wind tunnel measurements of formula car drag coefficient and airfoil lift, drag, and moment coefficients and instrumentation

ME 585 - Energy Systems Design Project

• Utilize a design methodology, including creative synthesis of solutions; evaluation of solutions based on criteria and constraints; sensitivity analysis; choice of “best” design
• Work effectively as part of a team
• Work with deadlines
• Communicate ideas
• Defend his/her decisions

• Thermodynamics
• Fluid mechanics
• Heat transfer

• Outline of design process; project assignments
• Problem statement
• Literature search techniques
• Brainstorming/list of solutions
• Criteria and constraints/criterion function
• Sensitivity analysis
• Oral presentation guidelines
• Report writing guidelines
• Oral presentations
• Team meetings with instructor
• Team project work
• Graduate students will be given additional assignments

ME 601 - Vibration Control

• Model simple vibratory systems and determine equations of motion
• Solve equations of motion for single degree of freedom systems subject to harmonic, general periodic and arbitrary forcing functions
• Write equations of motion for idealized multi-degree of freedom systems
• Determine natural frequencies and mode shapes for systems with two and three degrees of freedom
• Develop appropriate analytical models for simulation using MATLAB w/ Simulink
• Perform measurements and conduct modal tests on simple systems

• Dynamics
• Calculus
• Differential equations
• Computer programming

• Review: modeling mechanical systems
• Review: solving differential equations - analytical, numerical methods
• Free vibration
• Harmonically excited vibration
• Fourier series, periodic functions
• Transient vibration
• Systems with two or more degrees of freedom
• Lagrange’s equation
• Vibration control
• Vibration measurement and applications
• Exams
• Graduate students will be given additional assignments

• Free and forced vibration demonstration and measurement on 1 and 2 DOF systems

ME 602 - Vehicle Dynamics

• Simulate acceleration and braking performance of common vehicles
• Model the normal road loads acting on vehicles
• Model and simulate suspension forces due to road inputs and steady state cornering forces
• Design and simulate common suspension and steering geometries
• Apply tire properties to vehicle performance

• Kinematics
• Dynamics of systems

• Introduction to modeling and dynamic loads
• Power and traction limited acceleration models
• Braking performance, forces, and systems
• Road loads, aerodynamic drag, and rolling resistance
• Ride and suspension models
• Steady state cornering, forces, and suspension effects
• Analysis of common suspensions
• Analysis of common steering systems
• Properties and construction of tires
• Safety ratings and roll-over propensity
• Review and testing
• Graduate students will be given additional assignments

ME 609 - Experimental Stress Analysis

• Understand concept of stress and strain
• Understand underlying principles in using strain gauges
• Mount strain gauges, take measurements and analyze the obtained data
• Design strain gauge-based transducers for measuring specific loads
• Understand basic principles of photoelasticity, and use it as an analysis tool
• Sources outside the class notes and text

• Intermediate mechanics of materials

• Review of states of stress
• State of strain at a point
• Principal strains and Mohr’s circle
• Electrical resistance strain gauges
• Strain gauge circuits
• Transducer design
• Exams
• Presentation of project by students

• Strain measurement on a cylindrical pressure vessel
• Strain gauge mounting practive
• Strain gauge mounting and soldering
• Strain measurements of lab projects
• Photoelasticity demonstration
• Photoelastic measurement

ME 621 - Corrosion and Degradation of Materials

• Identify the eight common forms of corrosion in metals, and environmental stress cracking in polymer-based materials
• Understand the interaction of processing, material and environment with regard to corrosion failures
• Understand the principles of electrochemical corrosion in regard to prevention and minimization of corrosion

• Basic metallurgy of steels, aluminum alloys and copper-based alloys
• Polymer structure and properties
• General chemistry
• Principles of atomic movement (diffusion)

• Electrochemical aspects of corrosion
• Galvanic corrosion
• Crevice and pitting
• Corrosion
• Intergranular corrosion
• Hydrogen damage and stress corrosion cracking
• Degradation of polymers
• Selective leaching
• Erosion corrosion
• Material selection and design
• Project meeting and presentations
• Exams

ME 622 - Fatigue and Fracture in Mechanical Design

• Understand the distinction between “high” cycle versus “low” cycle fatigue problems and correctly choose an appropriate analysis method for a design problem
• Understand cyclic plastic strain behavior and be able to apply mathematical models for cyclic plastic strain to design problems
• Apply strain-life methods for low cycles fatigue
• Combine notch-strain analysis using Neuber’s rule with low cycle fatigue analysis for component life predictions
• Understand basic concepts in Linear Elastic Fracture Mechanics (LEFM)
• Apply basic LEFM models to problems in 1) fracture of metals, 2) fatigue crack growth rate and 3) fail safe design

• Stress-Life approach to fatigue problems
• Mechanics of materials

• Review - fatigue basics, stress-life diagrams, stress concentrations, notch sensitivity, mean stress effects
• Multi-axial states of stress
• Variable amplitude load histories
• Low cycle fatigue (plastic strain cycling, 2 to 1000 cycle life)
• Cyclic stress-strain curves & plastic strain-life diagrams (ε-N diagrams)
• Notch strain analysis, Neuber’s rule
• Microscopic/material aspects of fatigue, fracture mechanics (LEFM, linear elastic fracture mechanics)
• Stress intensity factor & plane strain fracture toughness
• LEFM and fatigue crack growth rate, Paris’ law, numerical methods
• Failure analysis - observations on failed parts
• “Fail Safe” design practices

ME 683 - Computational Fluid Mechanics

• Have a fundamental understanding of the underlying PDEs for fluid flow
• Become familiar with various types of boundary conditions
• Set up, run, and interpret results of various flows in CFD
• Find good balance between time/computer resources and the output accuracy

• Fluid mechanics
• Numerical methods

• Governing equations of fluid dynamics
• Finite volume method for diffusion
• FVM for convection - diffusion
• TDMA
• FVM for unsteady flows - explicit and implicit
• Pressure - velocity coupling in steady flow
• SIMPLE
• SIMPLER
• Turbulence modeling
• Vorticity transport
• Course project
• Project discussion and presentations

ME 799 - MSE Independent Study

• Apply advanced mechanical engineering principles to complex problems

• Varies

• To be determined by faculty advisor

ME 822 - Structure and Properties of Engineering Materials

• Be familiar with the structure, properties and processing of ferrous alloys and aluminum alloys
• Be able to understand the structure, property and processing relationship in other alloy systems
• Explain the difference in composition, properties, processing and uses of iron-based alloys

• Basic atomic arrangement, including defects of crystalline materials
• Relationship between structure and properties for metals
• Mechanical properties

• Introduction and review
• Fundamentals of iron/carbon system
• Alloy steels
• Tool steels
• Cast iron)
• Stainless steels
• Aluminum alloys
• Other non-ferrous alloys
• Project meeting and presentations
• Exam and review

ME 823 - Powder Metallurgy

• Understand the technological and metallurgical principles of powder metallurgy
• Understand the correlation between process parameters and properties of P/M materials
• Characterize powders, understand the compacting and the sintering process
• Understand the effect of porosity on properties of P/M materials and the significant differences to properties of steel and other wrought materials
• Apply the most important criteria for designing P/M parts
• Understand the importance of the P/M process for material utilization and energy conservation

• Science of engineering materials

• Introduction, history of PM, definitions of P/M, P/M materials
• Powder fabrication: mechanical comminution, chemical reactions, liquid metal atomization, electrolytic deposition.
• Powder characterization: particle shape, size and distribution, surface area
• Powder preparation: mixing and blending, powder lubrication, flow, apparent density, compressibility
• Shaping and compacting: fundamentals of compacting, cold compacting with dies, design guidelines, isostatic compacting
• Sintering: fundamentals and sintering theory, mixed powder, liquid phase sintering, effect of sintering atmospheres, sintering furnaces
• Full density processing: enhanced sintering techniques, powder forging
• Properties of sintered steel: effect of density, alloying elements, and impurities
• Application of P/M materials: filter; bearings, structural parts, powder forged parts
• Experiments: powder characteristics, compressibility, sintering, mechanical properties, microstructure, scanning electron microscope

ME 860 - Advanced Mechanics

• Understand deformation and stress measures
• Ability to solve boundary value problems involving deformable solids
• Understand the basis for numerical methods in sold mechanics
• Idealize a system or component for stress analysis
• Use appropriate numerical and analytical means to model the system, interpret the results and draw conclusions
• Present results orally and in writing

• Strength of materials

• Stress in a solid
• Strain in a solid
• Elastic, plastic and viscoelastic behavior
• Boundary value problems for linear elastic solids
• Variational methods for elastic solids
• Finite element method
• Boundary value problems for elastic-plastic materials

ME 861 - Finite Element Analysis for Mechanical Engineering

• Apply finite element method in structural analysis (static and transient)
• Apply FEM in thermal analysis (fluids and heat transfer)

• Finite Element Method

• Review of FEA, steps in FEA (2 hours)
• Galerkin’s method of weighted residuals, beam element formulation (3 hours)
• Higher order element formulations, planar 2D analysis (2 hours)
• Dynamic analysis, lumped mass, explicit formulations (2 hours)
• Dynamic analysis, Rayleigh proportional damping, flow over a cylinder (3 hours)
• Thermal analysis, steady state conduction/convection, transient analysis (2 hours)
• Nonlinear analysis, geometric and material nonlinearities (2 hours)
• Design project (6 hours)
• Exams (4 hours)

• Modal analysis
• Transient axial and bending response in water tower design
• Nonlinear membrane analysis for pressurized plates

ME 862 - Advanced Mechanical System Design

• Design and analyze advanced machine components

• Machine components and design

• Design of nonpermanent joints
• Stresses in curved beams
• Brakes, clutches, and belt drives
• Springs
• Impact stresses
• Lubrication & journal bearings

ME 880 - Advanced Refrigeration

• Understand vapor compression refrigeration and select appropriate working fluid
• Understand thermodynamic processes with mixtures
• Design absorption refrigeration systems

• First and second laws of thermodynamics

• Review of related thermodynamics topics
• Vapor compression cycles
• Refrigerant properties
• Introduction/absorption cycle fundamentals
• Properties of working fluids
• Thermodynamics processes with mixtures
• Single-effect H20/LiBr systems
• Double-effect H20/LiBr systems
• Single-effect NH3/H20 systems
• Two-Stage NH3/H2o systems
• GAX cycles
• Review and exams

ME 881 - Building Energy Simulation

• Have a scientific foundation for understanding and implementing comprehensive building energy analysis procedures
• Perform energy analysis in developing an optimum HVAC and architectural design for new buildings, and in determining cost effective modifications to existing buildings
• Recognize the role and application of ASHRAE Standard 901, the basis of majority of building codes, and compliance software

• Thermodynamic and heat transfer

• Building Description Language (BDL) and using DOE-2 (this goes concurrently with the following topics)
• Design load calculation
• Diversified load calculation
• Air system component analysis
• Air system simulation
• Plant component simulation
• Life-cycle-cost (LCC)
• Parametric analysis

ME 882 - Compressible Flow

• Apply engineering principles and analyze problems dealing with compressible flow and gas dynamics
• Compare shock expansion with linearized theory for subsonic and supersonic flow over airfoils
• Design a supersonic nozzle using the method of characteristics

• Fluid mechanics
• Thermodynamics (covering II Law)

• Review of the fundamentals (laws of thermodynamics, conservation of mass, momentum and energy, entropy changes for perfect gases, stagnation properties)
• Introduction to compressible flow (sonic velocity, Mach number, stagnation relations in terms of Mach number, total pressure loss and entropy change relation, isentropic flow tables)
• Standing normal shocks
• Fanno flow and applications
• Rayleigh flow and applications
• Oblique shocks
• Prandtl-Meyer flow (including lift and drag calculations on airfoils at various angles of attack)
• Varying-area adiabatic flow (convergent-divergent nozzle, diffuser, choking)
• Supersonic nozzle experiment and Mach number calculations
• Topic: applications of compressible flow in propulsion systems (example: ramjet engine)
• Differential conservation equations
• Moving normal shock waves
• Velocity potential equation
• Linearized flow: subsonic and supersonic
• Conical flow
• Method of characteristics
• Finite difference techniques for steady supersonic flow

• Supersonic nozzle experiment

ME 884 - Numerical Methods in Heat Transfer

• Formulate and solve various conduction, convection and radiation problems
• Understand similarity transformation to convert PDEs to ODEs related to boundary flow problems
• Develop computer programs (in MATLAB) to solve several heat transfer problems
• Review and discuss journal papers in numerical heat transfer

• Heat transfer
• Fluid mechanics

• Heat transfer through a double-pane/triple-pane glass window
• Steady-state heat transfer through fin (rectangular, triangular)
• 2D heat conduction - explicit, implicit
• Unsteady heat conduction (example: radiation heating and cooling), semi-infinite solid
• Heat transfer through a circular duct
• Laminar flow over an isothermal flat plate (similarity-numerical, integral-approximate, direct numerical)
• Free convection heat transfer on a vertical flat plate (similarity-numerical RK scheme)
• Radiation - flat plate solar collector
• Radiation transfer in an enclosure - multiple surfaces
• Course project

• Fin heat transfer
• Free and forced convection

ME 885 - Transport Phenomena

• Apply correlation for viscosity and thermal conductivity
• Solve transport problems by specifying and applying initial and boundary conditions
• Develop steady-state shell balances for momentum and energy transport equations
• Apply equations of change to solve steady-state flow problems
• Apply equations of change to solve steady-state conduction and convection problems
• Solve transport problems with two independent variables, such as time-dependent flow of Newtonian fluids and unsteady state heat transfer

• Fluid mechanics
• Heat transfer

• Viscosity
• Thermal conductivity
• Mechanism of energy transport
• Shell momentum balances
• Flow through a circular tube, annulus
• Creeping flow around a sphere
• Shell energy heat conduction with heat sources
• Forced and free convection heat transfer
• The equation of continuity
• Equation of motion
• Equations of change to solve flow problems
• Dimensional analysis
• Equations of energy and motion
• Equations of change to solve heat flow problems
• Dimensional analysis
• Time dependent flow of Newtonian fluids
• Unsteady heat conduction in solids
• Steady heat conduction in laminar, incompressible flow
• Turbulent flow
• Turbulent momentum flux and flow in ducts
• Temperature distribution in turbulent flow
• Empirical expressions for turbulent heat flux
• Friction factors for flow in tubes
• Friction factors for flow around spheres
• Analytical calculations of heat transfer coefficient in tubes
• Forced convection in tubes
• Forced convection in around submerged objects

ME 5980 - Topics in Mechanical Engineering

• An ability to apply engineering principles to problems in a topic of mechanical engineering

• Consent of instructor

• This course allows for study of engineering topics in mechanical engineering that are not present in the curriculum. 
• Topics of mutual interest to faculty and students will be explored. 

MG 631 - Research and Writing (Module One)

• Fundamentally understand of the characteristics and differences associated with types of research (primary, secondary, and tertiary)
• Understand and apply in a research project, library and Internet research concepts, definitions, and strategies – including topic selection strategies
• Proficiently use bibliographic and full-text article databases to retrieve relevant source material for research and writing projects
• Proficiently use of bibliographic and full-text book databases – as well as bibliographic databases providing access to other types of information – to retrieve relevant source material for research and writing projects
• Discern credible research literature
• Understand the basic conventions and requirements associated with the writing and the organization of academic papers
• Apply the principles, requirements, and procedures associated with the proper documentation and formatting of academic research papers in compliance with the APA style manual
• Use REfWorks, the MSOE online bibliographic management system
• Apply academic integrity principles, concepts, and procedures in an academic research paper
• Express ideas in a clearly written brief academic research paper

• None 

• Types of research
• Library and Internet research principles, strategies, and expectations
• Library and Internet tools and resources for doing research and for managing research
• Publication Manual of the American Psychological Association (i.e., the APA style guide)
• RefWorks online bibliographic management system
• The academic paper versus “real-world” writing
• The organizational structure of an academic paper
• The writing of abstracts and executive summaries
• Plagiarism
• Basic grammar, punctuation, and writing tips

MG 632 - Research and Writing (Module Two)

• Express ideas clearly in written reports
• Eevelop and plan research strategies for studies and reports
• Conduct research using an array of research techniques including electronic ones
• Provide support and documentation for research
• Effectively communicate in groups, including participating in collaborative writing projects
• Demonstrate an understanding of the full range of communication media and various presentation techniques
• Demonstrate an understanding of the communication process and the role of audience

• None

• Organize and analyze a situation using case information along with personal knowledge and any research that may be required
• Identify, synthesize, and evaluate possible solutions
• Select, justify, and apply experience to a management-level problem

MG 633 - Research and Writing (Module Three)

• Express ideas clearly in written reports
• Develop and plan research strategies for studies and reports
• Conduct research using an array of research techniques including electronic ones
• Provide support and documentation for research
• Effectively communicate in groups, including participating in collaborative writing projects
• Demonstrate an understanding of the full range of communication media and various presentation techniques
• Demonstrate an understanding of the communication process and the role of audience

• None

• Selecting main ideas and research findings from others that relate to a research topic
• Analyzing research and identifying patterns and themes in the articles reviewed
• Integrating and combining ideas from source articles and drawing the ideas together into a thematically written research report
• Making distinctions about the quality of sources based on objectively defined criteria
• Documenting and support research
• Formatting and editing of reports

MG 8042a - Application Thesis - Cultural Immersion - Part 1

• Gain an understanding for the past, current and future importance of China within the global market
• Appreciate the demographic and economic implications of China in the global market
• Explore and discuss culture, history and politics to provide a backdrop for business with China
• Identify and appraise distinct global operating strategies and assess the implications of each
• Explore challenges and benefits to the China related to entry, growth and divestment
• Assess the relationship of market, product and global operation strategies
• Review a tiered market approach
• Explore the benefits and barriers to various business partnership models
• Discuss supply chain benefits and challenges
• Assess marketing strategies
• Explore sources of competition and how this has shifted
• Highlight tactics to reach Chinese consumers
• Understand the relationship of the local and central government to business
• Explore specific issues related to managing in China
• Compare and contrast challenges and strategies related to recruiting, developing and retaining employees at different levels of the organization
• Explore generational and regional differences, while assessing methods to motivate employees
• Review new laws related to employment
• Generate approaches to managing virtually
• Explore the role of the leader in China
• Identify and discuss ethical issues related to managing in China
• Identify legal and risk management issues related to doing business
• Cultivate a frame of mind for international servant leadership
• Understand importance of Guanxi to doing business
• Understand the roles of government and business organizations
• Develop professional networks through contacts established through the course
• Gain leadership experience to promote confidence, efficiency, and effectiveness in international business

• None

• None

MG 8042b - Application Thesis - Cultural Immersion - Part 2

• Gain an understanding for the past, current and future importance of China within the global market
• Explore and discuss culture, history and politics to provide a backdrop for business with China
• Identify and appraise distinct global operating strategies and assess the implications of each
• Assess marketing strategies
• Explore specific issues related to managing in China
• Identify and discuss ethical issues related to managing in China
• Identify legal and risk management issues related to doing business
• Cultivate a frame of mind for international servant leadership
• Understand importance of Guanxi to doing business
• Gain leadership experience to promote confidence, efficiency and effectiveness in international business

• None

• Learn dining etiquette
• Compare US and Chinese cultures
• Culture, business and religion training
• Chinese character, art and calligraphy lesson
• Practice bartering and negotiations
• Mergers and acquisition integration with multiple cultures
• Role of global corporate culture at local level
• Business etiquette
• Understanding legal issues in China
• Explore the role of US and China relationships in a world context
• Learn support networks of AmCham
• Technology for communication and surveillance
• Traditional Chinese medicine
• Chinese culture overview
• Servant leadership project

PE 647 - The Design of Experiments

• Calculate standard deviation, range, coefficient of variation, percentiles, and the assessment of normality within data sets
• Identify measurement scales (ratio, interval, ordinal, nominal) and their significance in statistical designs
• Identify and distinguish between independent and dependent variables within research studies
• Explain the concepts, calculations, and use associated with measures of sensitivity, specificity, positive and negative predictive values as they relate to diagnostic screening tests
• Formulate statistically testable hypotheses in both mathematical and English terms
• Explain the potential causes of Type I and Type II error and the interdependent influences of alpha, sample size, and effect size on statistical power
• Appropriately use the three variations of the t-test and how to test for compliance with their underlying assumptions
• Appropriately use fixed and repeated-measures ANOVA within research designs and test for their underlying assumptions
• Explain the structure, value, and interpretation of the ANOVA source table.
• Explain when and why multiple comparison tests are needed when performing an ANOVA
• Explain the advantages and disadvantages associated with repeated-measures designs
• Explain the concepts and use of correlation, single, multiple, polynomial, and logistic regression models - including knowing how to assess the fit and quality of these models
• Explain the value and use of basic nonparametric statistical tests
• Statistically, graphically, and completely evaluate and interpret raw experimental data sets
• Critically evaluate and properly assess the statistical designs and their underlying assumptions used within research studies

• None 

• Research concepts, descriptive statistics, hypothesis testing, diagnostic tests (2 class periods)
• Use and interpretation of the single-sample, paired, and unpaired t-test (1 class period)
• Use and interpretation of the fixed-effect and repeated-measures ANOVA; journal article critique (2 class periods)
• Correlation and regression analysis (3 class periods)
• Nonparametric statistical tests (chi-square, Mann-Whitney U, Kruskal-Wallis) (1 class period)

PE 650 - Seminar on Clinical Medicine

• Explain the theory and operation of intra-aortic balloon pumps
• Describe the history of VAD development and the theory of VAD operation
• List the specific VADs used at SLMC and explain the conditions under which each might be used.
• List risk factors associated with heart disease
• Describe the use of dialysis and hemofiltration for fluid management in the cardiac surgical patients
• Describe the use of ventilator support, inhaled Flolan and nitric oxide for managing patients with pulmonary dysfunction.
• Explain the uses of blood products for the treatment of hemodynamic and coagulative disorders.
• Explain the factors that are included in the assessments for transplant candidates
• Describe the use of UNOS and pre and post-operative care for transplant patients
• Explain the surgical management of transplant patients
• Describe the methods for control and monitoring of electrophysiological heart rhythms
• Clinical objectives
• Carry out the operation of IABPs
• Perform basic VAD management
• Perform patient training associated with home care and VADs
• Operate the Continuous Renal Replacement Therapy machine

• Knowledge of cardiovascular physiology and pathophysiology

• IABPs (2.5 classes)
• \VAD history and theory (1 class)
• VAD console operation (3.5 classes)
• Cardiac risk factors/pulmonary medicine (.5 class)
• Dialysis/ hemofiltration (.5 class)
• Blood conservation/blood products (.5 class)
• Transplantation (.5 class)
• Pacers/ (.5 class)

PE 670 - Pharmacology

• Explain the pharmacokinetics and pharmacodynamics of specific drug groups
• Describe the basic principles of peripheral nervous system pharmacology, provide examples of drugs from each class, and identify their mechanisms of action
• Describe the basic principles of cardiovascular and renal pharmacology, provide examples of drugs from each class, and identify their mechanisms of action
• Describe the basic principles of anticoagulants, provide examples of drugs from each class, and identify their mechanisms of action
• Describe the basic principles of anesthetic agents, provide examples of drugs from each class, and identify their mechanisms of action
• Describe the basic principles of chemotherapy of infectious agents, provide examples of drugs from each class, and identify their mechanisms of action
• Describe the basic principles of the pharmacological agents affecting the immune system, provide examples of drugs from each class, and identify their mechanisms of action
• Describe the basic principles of cancer chemotherapy, provide examples of drugs from each class, and identify their mechanisms of action

• Physiology and pathophysiology

• Basic principles of pharmacology (3 class periods)
• Autonomic nervous system drugs (5 class periods)
• Cardiovascular drugs (5 class periods)
• Anticoagulants (1 class period)
• Drugs for hyperlipidemia (1 class period)
• Anesthetics and skeletal muscle relaxants (2 class periods)
• Antimicrobial agents (4 class periods)
• Cancer chemotherapy and immunosuppressive agents (3 class periods)
• Drugs for diabetes and seizures (1 class period)
• Quizzes/exams (5 class periods)

PE 673 - Advanced Physiology I

• Explain the structural and functional properties of eukaryotic cells, and how gene expression affects these properties
• Explain the importance of movement of molecules across the cell membrane, the pathways for this movement and the factors that affect movement of these molecules
• Explain how membrane potentials are generated and predict the changes that will occur in membrane potentials when ion concentration or permeabilities change
• Identify the structures of the heart and name the major blood vessels
• Explain the physical principles and physiological processes that regulate function of the cardiovascular system
• Identify the waves of an EKG and explain what each wave represents
• Explain the feedback loops that are active in the control of arterial pressure
• Describe the steps involved in hemostasis, including the specific roles of platelets and clotting factors

• Undergraduate exposure to all topics

• Homeostasis and cell function (1.5 class periods)
• Cell membrane and transport mechanisms and genetics (1.5 class periods)
• Electrophysiology (3 class periods)
• Skeletal muscle structure and function (1.5 class periods)
• Smooth muscle structure and function (1.5 class periods)
• Heart anatomy and muscle function (1.5 class periods)
• Cardiac channels, pumps and exchangers (1.5 class periods)
• Rhythmical excitation of the heart (1.5 class periods)
• EKG (1.5 class period)
• Anatomy and physics of the circulation (3 class periods)
• Vascular distensibility (1.5 class periods)
• Microcirculation and lymphatics (1.5 class periods) 
• Local and nervous control of blood flow (1.5 class periods)
• Long-term regulation of arterial pressure (1.5 class periods) 
• Hemostasis (1.5 class period)
• Exams (4 class periods)

PE 674 - Advanced Physiology II

• Describe the components of the immune system and how they interact to functionally provide immune function
• Discuss the roles of the autonomic nervous system and endocrine system in homeostatic feedback loops
• Describe the body compartments, their relative sizes and how water moves between the compartments
• Describe the anatomy and physiology of the urinary system, including the regulation of GFR, functional aspects of the nephron and control of secretion and reabsorption that occurs along the nephron
• Discuss the mechanisms of acid/base balance and apply them to physiological situations
• Describe the anatomy and physiology of the respiratory system, including mechanisms for gas exchange and transport
• Describe the functions of the liver

• Undergraduate knowledge of all topics

• Immunity (4.5 class periods)
• Autonomic nervous system (1.5 class period)
• Endocrine system (1.5 class period)
• Body fluid compartments (1.5 class period)
• Urinary system (6 class periods)
• Acid/base balance (1.5 class periods)
• Respiratory system (6 class periods)
• Liver (1.5 class periods)
• Exams (5 class periods)

PE 675 - Pathophysiology

• Explain the cellular basis of disease and the causes of cellular injury
• Describe the vascular changes that occur with acute and chronic inflammation and list the mediators of the vascular changes
• Describe the processes involved in tissue repair and regeneration
• Describe the cells and mediators involved in immunity, their roles and how they are regulated
• Describe the types of hypersensitivity reactions of the immune system and how they might develop
• Describe the alterations that can occur in hemostasis and in delivery of blood flow, their manifestations and treatments
• Describe the types, manifestations, and treatments of circulatory shock and coronary artery disease
• Describe the types, manifestations, and treatments of valvular disorders, heart failure and cardiac arrhythmias
• Describe the types, manifestations, and treatments of pericardial diseases and anemias
• Describe the types, manifestations, and treatments of fluid and electrolyte disorders and acid/base disorders
• Describe the types, manifestations, and treatments of intrarenal disorders and renal failure
• Describe the types, manifestations, and treatments of respiratory disorders
• Describe the types, manifestations, and treatments of endocrine disorders

• An understanding of anatomy and physiology of the systems covered

• Cell injury, aging, and death (1 class)
• Acute and chronic inflammation (1 class)
• Immune system and immune system dysfunction (2 classes)
• Alterations in hemostasis and hemodynamic disorders (1 class)
• Circulatory shock (1 class)
• Coronary artery disease and coronary catheterization (1 class)
• Valvular heart disease and heart failure (1 class)
• Hypertension and cardiac arrythmias (1 class)
• Pericardial disease, anemias and transfusions (1 class)
• Fluid and electrolyte disorders and acid/base disorders (1 class)
• Intrarenal disorders (1 class)
• Renal failure (1 class)
• Respiratory disorders (1.5 classes)
• Endocrine disorders (1.5 classes)
• Exams (3 classes)

PE 699 - Master’s Thesis

• Perform a literature search using Medline or similar search engines
• Summarize background literature in a manner that culminates in a reasonable hypothesis
• Perform a study, experiment, or design to address the hypothesis
• Summarize, appropriately interpret and present study findings
• Make reasonable conclusions as to the applicability of their findings
• Present their background, study, and results in both written and oral format

• None

• Vary

PE 7001 - Special Situations in Perfusion Practice

• Anticipate, identify, and safely handle catastrophic events that may occur in the perioperative period.
• Prepare for procedures such as off pump coronary artery bypass grafting, minimally invasive direct coronary artery bypass grafting, transmyocardial laser revascularization, lead extractions, pump standbys, etc.
• Apply the various techniques associated with on-pump minimally invasive procedures such as robotic-assisted and port access
• Employ the techniques and considerations associated with left and right-heart bypass procedures
• Explain the circuits, techniques, and considerations associated with cardiopulmonary support in the urgent setting
• Safely utilize vacuum and kinetic-assisted venous drainage during CPB
• Employ interventions to minimize air introduction into the CPB circuit
• Explain the negative effects of air emboli in patients
• Describe the role of perfusionists in emergency preparedness
• Understand the specifications and operating parameters of various pieces of perfusion equipment and components

• None

PE 7011 - Clinical Extracorporeal Perfusion I

• Describe the clinical instruction process of the MSP program
• Articulate student expectations of the MSP program
• Explain the scope of practice of a perfusionist
• Explain the history and developmental milestones of cardiopulmonary bypass
• Explain and employ aseptic techniques in the operating room
• Describe how the typical cardiovascular surgical patient presents
• Explain the standard monitoring of surgical cardiac patients
• Describe the conduct of perfusion, from initiation through termination of cardiopulmonary bypass
• Identify and use the equipment necessary to perform cardiopulmonary bypass
• Describe the physiological theory of cardiopulmonary bypass
• Demonstrate basic literature review skills

• None

PE 7015 - Perfusion Simulation I

• Set up a CPB circuit
• Prime the CPB circuit
• Go on and come off bypass

• None

PE 7016 - Perfusion Simulation II

• The fundamental skills of going on and coming off bypass, running the middle of a straight-forward CPB case, and running cardioplegia
• The ability to interpret anticoagulation and blood gas analysis testing
• The ability to troubleshoot minor issues with the CPB circuit

• Basic use of the simulator, including how to use it to practice going on pump and coming off pump

PE 7017 - Perfusion Simulation III

• Go on and come off bypass, running the middle of a straight-forward CPB case, running the middle of a trouble-ridden CPB case, and running cardioplegia
• Interpret anticoagulation and blood gas analysis testing and troubleshoot any issues with these lab values
• Troubleshoot major issues with the CPB circuit

• Ability to use the simulator to run a straightforward case.

PE 7022 - Clinical Extracorporeal Perfusion II

• Identify the components of various priming solutions and explain the situations in which common priming solutions are used
• Explain the benefits and disadvantages of hemodilution during CPB
• Explain the theoretical underpinnings and practical applications of myocardial protection
• Describe the various solutions and arrest methods utilized for cardioplegia
• Describe the various delivery routes for cardioplegia administration and the benefits and drawbacks for each.
• Diagram the coagulation cascade and complement system
• Describe the role of platelets in normal physiology and how they are impacted during CPB
• Discuss challenges resulting from blood surface interface and ways to minimize its detrimental effects
• Exhibit knowledge of the pharmacology of anticoagulants and procoagulants
• Diagnose heparin resistance and differentiate it from antithrombin III deficiency
• Discuss the mechanism of heparin induced thrombocytopenia (HIT) and explain how to manage this type of patient during CPB
• Explain the process and possible deleterious effects of heparin neutralization via protamine sulfate (e.g. protamine reactions and treatment options)
• Discuss the impact of CPB on the following systems: pulmonary, renal, splanchnic, hepatic, viscera, and neurological
• Describe the endocrine, metabolic, and electrolyte responses to CPB
• Describe the immune and inflammatory responses associated with CPB

• None 

PE 7031 - Clinical Extracorporeal Perfusion III

• Identify and discuss the characteristics of various blood tests
• Exhibit an understanding of the effect CPB has on various electrolytes and identify the corresponding tests to monitor the value of each
• Compare and contrast the various tests used to assess the coagulation system and interpret test results in the context of patient clinical history
• Discuss the monitoring techniques utilized during the perioperative period
• Recognize and treat physiological differences between various patients, their disease states, and the type of surgical procedure they may undergo
• Explain the physiology of myocardial protection, the determinants of appropriate myocardial preservation, and the technical details of cardioplegia administration
• Discuss the characteristics and components of various cardioplegia solutions and subsequent delivery techniques
• Describe the implications of blood product administration, as well as explain techniques to avoid utilizing blood products
• Describe the theory behind pulsatile perfusion and the clinical implications of its application
• Explain the clinical uses of hypothermia, including its beneficial and adverse effects
• Describe the perfusion techniques utilized for thoracic aortic surgery
• Exhibit an understanding of ECMO and its application to the adult population

• None

PE 7042 - Pediatric Extracorporeal Perfusion

• Understand fetal, neonatal, and pediatric anatomy/physiology
• Gain knowledge and understanding of the various congenital heart defects, the sequelae associated with them, and the procedures utilized to treat them
• Understand the preoperative course of the pediatric patient
• Gain knowledge of the anesthetic strategies employed during surgery
• Understand the various considerations concerning cardiopulmonary bypass (CPB) circuits, and management during bypass including myocardial protection
• Gain knowledge of the techniques of hypothermia and circulatory arrest
• Gain knowledge of the neurological effects of CPB, and an understanding of the particular neuro-protective strategies that are used in the pediatric setting
• Understand the application of extracorporeal membrane oxygenation (ECMO) in the pediatric setting
• Gain knowledge of the various circulatory assist devices used in pediatrics

• None 

PE 7052 - Clinical Extracorporeal Perfusion IV

• Demonstrate knowledge of malignant hyperthermia: symptoms, predisposing conditions, and considerations for CPB
• Demonstrate knowledge of how to manage a pregnant patient undergoing CPB
• Manage patients with sickle cell trait or disease undergoing various procedures requiring CPB
• Demonstrate knowledge of heparin-induced thrombocytopenia and how a patient with this condition could be managed during CPB
• Describe pertinent details of heart and lung transplants, including donor and recipient selection, operative techniques, and outcomes
• Exhibit an understanding of the various techniques of isolated limb perfusion (e.g. the associated patient populations, how to manage the application of it, and be able to assess the therapy for any potential problems)
• Discuss the management of plasmapheresis
• Demonstrate understanding of the theory behind autologous platelet gel and bone marrow aspirate, and exhibit the skills to perform the sequestration and concentration steps of these technologies
• Apply database and outcomes management techniques in order to take a “best practices” approach to perfusion
• Exhibit the team skills necessary for the practice of perfusion.
• Discuss the role of CQI in perfusion health care
• Discuss the requirements of HIPAA and apply the steps necessary to remain compliant
• Demonstrate knowledge of the business and legal aspects of perfusion (e.g. understanding the agencies with regulatory oversight over the domain of perfusion, as well as, the necessity to comply with employing institutions’ policies and procedures)
• Articulate the requirements to become a CCP, including the requirements necessary to participate in each part of the exam
• Prepare a cover letter and resume for each job application
• Discuss the steps commonly associated with the job interview process and contract negotiations.

• Simulation
• Perfusion practice in non-complicated patients

PE 7101 - Clinical Perfusion Practicum I

• Navigate ASLMC and the operating room environment and articulate the roles of the operating room personnel, the locations of equipment and supplies, stay compliant with OSHA policies, and function within a sterile environment
• Demonstrate an understanding of the surgical patient with respect to the normal course to surgery, surgical preparation, monitoring, procedure(s), ICU transition, and postoperative course
• Acquire a general familiarity with the basic CPB pump components, supplies, and ancillary equipment
• Communicate details about the CPB circuit, including operational characteristics, inspection and evaluation of equipment and supplies, assembling a CPB back-up circuit, and priming
• Demonstrate advanced understanding of the patient with respect to history, physical, and cardiac catheterization lab and blood gas data
• Implement a pre-bypass checklist and surgical/CPB plan and routine
• Exhibit an ability to participate in patient charting and some basic perfusion tasks during surgery

• None 

PE 7102 - Clinical Perfusion Practicum II

• Exhibit mastery of circuit set-ups, priming, and preparation for bypass
• Exhibit familiarity during surgery with the specific details of patient monitoring, cannulation, and blood gas/anticoagulation monitoring
• Perform additional basic perfusion tasks as allowed by the instructor
• Postoperatively monitor the patient status, participate in blood salvage procedures, disassemble/dispose of the used circuit, disinfect the pump console, and set up the circuit for the next procedure
• Prepare the CPB circuit based upon the surgical and CPB plan
• Assume the responsibilities as the “primary perfusionist”–initiate CPB, operate ancillary pump components, manage the patient’s hemodynamics, volume status, blood gases, anticoagulation, and temperature, all while maintaining circuit and procedural awareness
• Wean the patient from bypass and monitor them and the pump until the end of the procedure

• None

PE 7103 - Clinical Perfusion Practicum III

• Act as the “primary perfusionist,” as demonstrated by proficiency in the practice of perfusion technology and a progressively more independent nature
• Function in cases with increasing difficulty with regard to technical complexity
• Apply advanced pharmacology concepts as learned in the didactic portion of this quarter

• None

PE 7106 - Clinical Perfusion Practicum VI

• Manage cases with minimal (or no) instructor intervention
• Demonstrate a complete understanding of the monitoring and techniques associated with adequacy of perfusion
• Demonstrate advanced perfusion techniques/practices and troubleshooting
• Exhibit an understanding of special perfusion situations and the specifics regarding catastrophic event management
• Function on-call on pre-appointed weekends (Friday 1600 - Monday 0600)

• None

PE 7114 - Clinical Perfusion Practicum IV

• Act as the “primary perfusionist” as demonstrated by proficiency in the practice of perfusion technology in a progressively more independent nature
• Demonstrate more advanced perfusion techniques
• Take part in ancillary tasks such as platelet gel preparation and non-cardiac support
• Apply advanced pharmacology concepts as learned in previous quarters
• Function on-call on pre-appointed weekends (Friday 1600 - Monday 0600).

• None

PE 7115 - Clinical Perfusion Practicum V

• Act as the “primary perfusionist” by demonstrating proficiency in the practice of perfusion technology in a progressively more independent nature
• Demonstrate more advanced perfusion techniques.
• Take part in ancillary tasks such as platelet gel preparation, non-cardiac support, blood gas analysis/monitoring, coagulation assessment/monitoring, intra-aortic balloon pumps, autotransfusion, and ventricular assist devices
• Function “on-call” on pre-appointed weekends (Friday 1600 - Monday 0600)
• Demonstrate an understanding of the specific details about the pediatric CPB circuit(s), including operational characteristics, inspection and evaluation of equipment and supplies, assembling a CPB circuit, and priming
• Participate in circuit set-up, priming, and preparation for bypass, as allowed by the instructor
• Create a perfusion plan for the of the pediatric patient by incorporating history, physical, and cardiac catheterization lab and blood gas data
• Implement a pre-bypass checklist and review the surgical/CPB plan and routine
• Participate in patient charting and some basic perfusion tasks as allowed by the instructor
• Exhibit an understanding of the details of patient monitoring, cannulation, and blood gas/anticoagulation monitoring, with respect to the pediatric patient
• Monitor the patient status, participate in blood salvage procedures, disassemble/dispose of the used circuit, and disinfect the pump console after the procedure
• Participate in on-call activities that do not interfere with class
• Wean the patient from bypass, utilize modified ultrafiltration, and monitor the patient and the pump until the end of the procedure, as allowed by the instructor

• None 

SE 5980 - Topics in Software Engineering

• Varies

• Varies

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SE 5981 - Topics in Software Engineering with Lab

• Varies

• Varies

• Varies

• Varies