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May 05, 2024
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PE 675 - Pathophysiology3 lecture hours 0 lab hours 3 credits
Course Description
This course is designed to cover the pathological processes that most directly relate to cardiovascular perfusion. Areas covered include: cell and tissue injury and healing, immunology and immunopathology, alterations in hemostatsis, and vascular, cardiac, renal, respiratory and endocrine dysfunction and disorders. (prereq: PE-673)
Course Learning Outcomes
Upon successful completion of this course, the student will be able to:
Explain the cellular basis of disease and the causes of cellular injury. • Describe the vascular changes that occur with acute and chronic inflammation and list the mediators of the vascular changes. • Describe the processes involved in tissue repair and regeneration. • Describe the cells and mediators involved in immunity, their roles and how they are regulated. • Describe the types of hypersensitivity reactions of the immune system and how they might develop. • Describe the alterations that can occur in hemostasis and in delivery of blood flow, their manifestations and treatments. • Describe the types, manifestations and treatments of circulatory shock and coronary artery disease. • Describe the types, manifestations and treatments of valvular disorders, heart failure and cardiac arrhythmias. • Describe the types, manifestations and treatments of pericardial diseases and anemias. • Describe the types, manifestations and treatments of fluid and electrolyte disorders and acid/base disorders • Describe the types, manifestations and treatments of intrarenal disorders and renal failure. • Describes the types, manifestations and treatments of respiratory disorders. • Describe the types, manifestations and treatments of endocrine disorders.
Prerequisites by Topic
And understanding of anatomy and physiology of the systems covered.
Course Topics
Cell injury, aging and death (1 class) • Acute and chronic inflammation (1 class) • Immune system and immune system dysfunction (2 classes) • Alterations in hemostasis and hemodynamic disorders (1 class) • Circulatory shock (1 class) • Coronary artery disease and coronary catheterization (1 class) • Valvular heart disease and heart failure (1 class) • Hypertension and cardiac arrythmias (1 class) • Pericardial disease, anemias and transfusions (1 class) • Fluid and electrolyte disorders and acid/base disorders (1 class) • Intrarenal disorders (1 class) • Renal failure (1 class) • Respiratory disorders (1.5 classes) • Endocrine disorders (1.5 classes) • Exams (3 classes)
Laboratory Topics
None appended
Coordinator
Ronald Gerrits
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